Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432696 | 0.89 | IDO1 (0.41) | ALDH1A1CYP3A4IDO1RAPGEF4 | |
| SCHEMBL4439316 | 0.86 | ALKBH3 (0.34) | RAPGEF4S1PR4TP53AGTR1 | |
| SCHEMBL4440097 | 0.86 | IDO1 (0.39) | CYP3A4IDO1RAPGEF4S1PR4 | |
| SCHEMBL4553496 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1HPGDKMT2ATDP1 | |
| SCHEMBL4436863 | 0.83 | AGPAT2 (0.37) | CYP3A4IDO1 | |
| SCHEMBL4433660 | 0.83 | MAOA (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4432361 | 0.80 | ALDH1A1 (0.33) | ALDH1A1HPGDCYP3A4LMNAAGTR1 | |
| SCHEMBL4429822 | 0.80 | ACHE (0.43) | ALDH1A1MEN1HPGDKMT2ACYP3A4 | |
| SCHEMBL4431199 | 0.80 | NOTUM (0.43) | — | |
| SCHEMBL9523594 | 0.80 | NPC1 (0.40) | ALDH1A1MEN1HPGDKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |