Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 5/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439151 | 0.86 | NOTUM (0.43) | NOTUMPDE2AMCL1PTGDR2 | |
| SCHEMBL4439285 | 0.84 | PDE2A (0.39) | PDE2AMCL1AHR | |
| SCHEMBL4432696 | 0.83 | IDO1 (0.41) | NOTUMAGPAT2 | |
| SCHEMBL4563986 | 0.81 | L3MBTL1 (0.36) | PDE2AMCL1PTGDR2TMPRSS4AHR | |
| SCHEMBL4429951 | 0.81 | KCNQ3 (0.42) | CETPPTGDR2 | |
| SCHEMBL4427424 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL4436863 | 0.78 | AGPAT2 (0.37) | AGPAT2 | |
| SCHEMBL4429675 | 0.77 | PDE2A (0.39) | PDE2AMCL1HSD11B1 | |
| SCHEMBL4432361 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL4062697 | 0.75 | KIF11 (0.41) | NOTUMTMPRSS4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |