Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432696 | 0.89 | IDO1 (0.41) | IDO1CYP3A4RAPGEF4AGPAT2L3MBTL1 | |
| SCHEMBL4607250 | 0.86 | S1PR4 (0.36) | IDO1RAPGEF4S1PR4 | |
| SCHEMBL4427424 | 0.86 | ALDH1A1 (0.35) | IDO1CYP3A4RAPGEF4S1PR4 | |
| SCHEMBL4553496 | 0.85 | ALDH1A1 (0.39) | RAPGEF4S1PR4KDM4E | |
| SCHEMBL9648679 | 0.83 | L3MBTL1 (0.40) | IDO1CYP3A4RAPGEF4AGPAT2L3MBTL1 | |
| SCHEMBL8527936 | 0.82 | HSD11B1 (0.43) | CYP3A4KDM4EPOLB | |
| SCHEMBL4439277 | 0.79 | ALDH1A1 (0.36) | RAPGEF4AGPAT2S100A4 | |
| SCHEMBL4436863 | 0.76 | AGPAT2 (0.37) | IDO1CYP3A4AGPAT2 | |
| SCHEMBL4436934 | 0.76 | ALDH1A1 (0.35) | RAPGEF4L3MBTL1KDM4E | |
| SCHEMBL3912578 | 0.76 | NPC1 (0.35) | CYP3A4L3MBTL1KDM4ENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |