Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28346642 | 0.96 | MT-CO2 (0.56) | MT-CO2KDM4EALDH1A1HPGDPTGS1 | |
| SCHEMBL12447795 | 0.83 | HPGD (0.71) | KDM4EALDH1A1HPGDMEN1LMNA | |
| Hydrochloric Acid SCHEMBL11570162 | 0.82 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL4427765 | 0.80 | CHRM1 (0.54) | MT-CO2KDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL29481378 | 0.80 | CHRM1 (0.54) | MT-CO2KDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL12608894 | 0.79 | MT-CO2 (0.60) | MT-CO2ALDH1A1PTGS1PTGS2MEN1 | |
| Hydrochloric Acid SCHEMBL2584597 | 0.79 | CHRM1 (0.53) | MT-CO2KDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL3810321 | 0.78 | PTGS2 (0.76) | MT-CO2KDM4EALDH1A1HPGDPTGS1 | |
| SCHEMBL9262003 | 0.77 | PTGS2 (0.69) | MT-CO2ALDH1A1HPGDPTGS1PTGS2 | |
| SCHEMBL10310896 | 0.77 | MT-CO2 (0.58) | MT-CO2PTGS1PTGS2MEN1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | MT-CO2 4662/4885KDM4E 4795/4885ALDH1A1 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.