Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | HMBS | P08397 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892342 | 0.87 | KDM4E (0.48) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL12930250 | 0.87 | KDM4E (0.42) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL4419322 | 0.84 | PIM3 (0.41) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL21983724 | 0.83 | KDM4E (0.44) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL15045615 | 0.81 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL7915531 | 0.79 | ALDH1A1 (0.66) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL15045557 | 0.79 | CYP2A6 (0.45) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL15045445 | 0.79 | KEAP1 (0.47) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL15045563 | 0.78 | CCR1 (0.54) | KDM4ESMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL13561660 | 0.78 | CYP1A2 (0.46) | KDM4ESMN1; SMN2HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | claimed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | claimed |
| US-9796705-B2 | Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170008879-A1 | FUSED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2017-01-12 | — | — | US | disclosed |
| US-9169282-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-9169282-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20130156731-A1 | FUSED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEAS | SCHERING CORPORATION | 2013-06-20 | — | — | US | disclosed |
| EP-2523243-A1 | Membrane-electrode assembly and fuel battery using the same | Sumitomo Chemical Company, Limited (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20100086823-A1 | MEMBRANE-ELECTRODE ASSEMBLY AND FUEL BATTERY USING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| US-20100086823-A1 | MEMBRANE-ELECTRODE ASSEMBLY AND FUEL BATTERY USING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1720615-B1 | COSMETIC HAIR DYEING COMPOSITIONS CONTAINING THEM AND USE THEREOF | PROCTER & GAMBLE (US) | 2009-12-30 | — | — | EP | disclosed |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| US-7468080-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | WELLA OPERATIONS US, LLC | 2008-06-12 | — | — | US | disclosed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1720615-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005087187-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | KDM4E 1418/4885SMN1; SMN2 4828/4885HTT 2703/4885 |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | KDM4E 1418/4885SMN1; SMN2 4828/4885HTT 2703/4885 |
| US-20110284799-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885SMN1; SMN2 3736/4885HTT 1979/4885 |
| US-20130156731-A1 | FUSED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEAS | HAVCR2, ELOC, ZC3HAV1 | KDM4E 2635/4885SMN1; SMN2 1324/4885HTT 511/4885 |
| US-20170008879-A1 | FUSED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | ZC3HAV1, HAVCR2, ZC3HAV1L | KDM4E 2910/4885SMN1; SMN2 957/4885HTT 728/4885 |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | MT-CO1, CYC1, ACAD9 | KDM4E 4791/4885SMN1; SMN2 2372/4885HTT 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.