Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431199 | 0.86 | NOTUM (0.43) | NOTUMPTGDR2PDE2AMCL1 | |
| SCHEMBL4429675 | 0.84 | PDE2A (0.39) | KIF11PDE2AMCL1CYP1A2 | |
| SCHEMBL4429907 | 0.84 | KIF11 (0.36) | NOTUMKIF11GPR3CYP1A1CYP1B1 | |
| SCHEMBL4432021 | 0.82 | CETP (0.39) | KIF11PTGDR2PDE2APDE10A | |
| SCHEMBL4553496 | 0.81 | ALDH1A1 (0.39) | RAPGEF4CYP1A2 | |
| SCHEMBL10689602 | 0.78 | KIF11 (0.39) | KIF11CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL4439277 | 0.75 | ALDH1A1 (0.36) | RAPGEF4 | |
| SCHEMBL4440097 | 0.75 | IDO1 (0.39) | NOTUMRAPGEF4JAK2 | |
| SCHEMBL8327759 | 0.74 | IKBKB (0.41) | NOTUMRAPGEF4NFE2L2CYP1A2 | |
| SCHEMBL4437593 | 0.74 | NOTUM (0.43) | NOTUMKIF11PTGDR2PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |