Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430185 | 0.93 | NPC1 (0.44) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL7097844 | 0.92 | LTA4H (0.44) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL8668313 | 0.89 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL17212283 | 0.88 | NPC1 (0.40) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL7100996 | 0.87 | NPC1 (0.46) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL17831410 | 0.87 | LMNA (0.39) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL7097913 | 0.87 | LMNA (0.39) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL23784451 | 0.85 | LMNA (0.37) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL5752606 | 0.85 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL28638598 | 0.84 | LMNA (0.40) | ALDH1A1CYP3A4CA2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743309-B1 | o-Hydroxyphenyl-s-triazines as UV stabilisers | CIBA SC HOLDING AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| EP-0654469-B1 | Stabilised polymers containing o-hydroxyphenyl-s-triazines | CIBA SC HOLDING AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| US-5591850-A | STABILIZERS FOR TEXTILE FIBERS, COSMETIC SUNSCREENS | CIBA-GEIGY CORPORATION (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0743309-A1 | o-Hydroxyphenyl-s-triazines as UV stabilisers | CIBA-GEIGY AG (CH) | 1996-11-20 | — | — | EP | disclosed |
| EP-0654469-A1 | O-Hydroxyphenyl-s-triazines as stabilisers for polymers | CIBA-GEIGY AG (CH) | 1995-05-24 | — | — | EP | disclosed |