Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658752 | 0.82 | NR3C1 (0.34) | NR3C1NR3C2PGRNR1H2NR1H3 | |
| SCHEMBL3684124 | 0.79 | CYP19A1 (0.36) | NR3C1NR3C2PGRCNR1CNR2 | |
| SCHEMBL4430202 | 0.76 | TAAR1 (0.44) | NR3C1NR3C2PGRNR1H2NR1H3 | |
| SCHEMBL4452422 | 0.73 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL3683919 | 0.73 | NR3C1 (0.42) | NR3C1NR3C2PGR | |
| SCHEMBL14159637 | 0.72 | NR3C1 (0.40) | NR3C1NR3C2PGR | |
| SCHEMBL4430210 | 0.70 | PDK1 (0.43) | NR3C2CNR1CNR2NR1H2 | |
| SCHEMBL12126413 | 0.70 | PGK1 (0.42) | PGK1PGK2CA2 | |
| SCHEMBL3684692 | 0.69 | NR3C2 (0.43) | NR3C1NR3C2 | |
| SCHEMBL3680388 | 0.69 | NR3C1 (0.56) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203160-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | Bausch & Lomb Incorporated (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009042377-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | BAUSCH & LOMB INCORPORATED (US) | 2009-04-02 | — | — | WO | disclosed |