Phthalic Acid

Phthalic Acid

SCHEMBL4430760

O=C(O)c1ccccc1C(=O)O.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
ALOX15 P16050 1/20 0.70
KMT2A Q03164 1/20 0.59
FFAR1 O14842 1/20 0.58
KEAP1 Q14145 1/20 0.56
AKR1C3 P42330 1/20 0.54
APEX1 P27695 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
HMGB1 P09429 1/20 0.52
HPGD P15428 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL28192884 0.89 TDP1 (0.70) ALDH1A1ALOX15KMT2AFFAR1KEAP1
Salicylic Acid SCHEMBL8746438 0.87 ALDH1A1 (0.75) ALDH1A1ALOX15FFAR1KEAP1SMN1; SMN2
SCHEMBL27331130 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15KMT2AFFAR1KEAP1
SCHEMBL29975597 0.87 FOLH1 (0.66) ALDH1A1ALOX15KMT2ASMN1; SMN2KDM4E
Salicylic Acid SCHEMBL8669345 0.87 ALDH1A1 (0.75) ALDH1A1ALOX15FFAR1KEAP1SMN1; SMN2
SCHEMBL166927 0.87 FOLH1 (0.66) ALDH1A1ALOX15KMT2ASMN1; SMN2KDM4E
SCHEMBL5590930 0.85 LCK (0.55) ALDH1A1ALOX15KMT2AFFAR1KEAP1
SCHEMBL8647436 0.85 G6PD (0.57) ALDH1A1ALOX15KMT2AFFAR1KEAP1
Hydrochloric Acid SCHEMBL7699238 0.85 FOLH1 (0.63) ALDH1A1ALOX15KMT2ASMN1; SMN2KDM4E
SCHEMBL1992489 0.85 KEAP1 (0.57) ALDH1A1ALOX15KMT2AFFAR1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644437-A4 LOW GLOW OLEFIN FERRO CORP (US) 2009-02-18 EP disclosed
EP-1599544-A4 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORP (US) 2007-05-02 EP disclosed
US-7176607-B2 Light fixture with reflective polymeric composition and pigment package FERRO CORPORATION (US) 2007-02-13 US disclosed
EP-1579147-A4 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORP (US) 2006-05-17 EP disclosed
EP-1644437-A1 LOW GLOW OLEFIN FERRO CORPORATION (US) 2006-04-12 EP disclosed
US-7026391-B2 Polymer compositions comprising polyolefins and reaction products of a polyolefin and an unsaturated carboxylic reagent and articles made therefrom FERRO CORPORATION (US) 2006-04-11 US disclosed
EP-1599544-A1 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORPORATION (US) 2005-11-30 EP disclosed
EP-1579147-A1 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORPORATION (US) 2005-09-28 EP disclosed
US-20050095534-A1 Light reflecting polymeric compositions FERRO CORPORATION (US) 2005-05-05 US disclosed
WO-2005007736-A1 LOW GLOW OLEFIN FERRO CORPORATION (US) 2005-01-27 WO disclosed
US-20050014888-A1 Low gloss olefin FERRO CORPORATION (US) 2005-01-20 US disclosed
US-6838494-B2 Light reflecting polymeric compositions FERRO CORPORATION (US) 2005-01-04 US disclosed
WO-2004078848-A1 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORPORATION (US) 2004-09-16 WO disclosed
WO-2004061366-A1 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORPORATION (US) 2004-07-22 WO disclosed
US-6759474-B1 POLYAMIDE, POLYPROPYLENE AND BLOCK COPOLYMER INCLUDING VINYL AROMATIC, CONJUGATED DIENE AND UNSATURATED DICARBOXYLIC MONOMERS; DROP IMPACT STRENGTH FERRO CORPORATION 2004-07-06 US disclosed
US-20040125603-A1 Light reflecting polymeric compositions FERRO CORPORATION 2004-07-01 US disclosed
US-20030004245-A1 Polymer compositions comprising polyolefins and reaction products of a polyolefin and an unsaturated carboxylic reagent and articles made therefrom LYONDELLBASELL ADVANCED POLYMERS INC. 2003-01-02 US disclosed
US-5317059-A Impact-resistant polymer blends of olefin polymers, polyamides, and terpolymer compatibilizers FERRO CORPORATION (US) 1994-05-31 US disclosed
US-5278231-A Comprising hydrogenated block copolymer FERRO CORPORATION (US) 1994-01-11 US disclosed
WO-1992022607-A1 HIGH SURFACE ENERGY POLYOLEFIN BLEND COMPOSITIONS THE FERRO CORPORATION (US) 1992-12-23 WO disclosed