Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431943 | 1.00 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ACYP1A1 | |
| SCHEMBL3993756 | 0.81 | NFE2L2 (0.58) | MAPTALDH1A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL3993752 | 0.81 | NFE2L2 (0.58) | MAPTALDH1A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL13528990 | 0.79 | CYP1A2 (0.62) | MAPTALDH1A1MEN1KMT2ACYP1A1 | |
| SCHEMBL2092229 | 0.79 | CYP1A2 (0.70) | MAPTALDH1A1MEN1KMT2ACYP1A1 | |
| SCHEMBL2092230 | 0.79 | CYP1A2 (0.70) | MAPTALDH1A1MEN1KMT2ACYP1A1 | |
| SCHEMBL6119425 | 0.78 | ABCG2 (0.55) | MAPTALDH1A1MEN1KMT2ACYP1A1 | |
| SCHEMBL79457 | 0.77 | MAPT (0.79) | MAPTALDH1A1MEN1KMT2ACYP1A1 | |
| SCHEMBL16710517 | 0.77 | NPC1 (0.65) | NPC1RAB9ABACE1CYP3A4HDAC6 | |
| SCHEMBL2090583 | 0.77 | CYP1A2 (0.68) | MAPTALDH1A1MEN1KMT2ACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541454-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541454-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541454-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20050159606-A1 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2005-07-21 | — | — | US | disclosed |
| WO-2005040357-A2 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | EPOCH BIOSCIENCES, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159606-A1 | Compounds and methods for fluorescent labeling | TFEB, HLCS, PFAS | MAPT 1854/4885ALDH1A1 514/4885MEN1 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.