Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 5/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421572 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1GLA | |
| SCHEMBL13492005 | 0.78 | DHODH (0.54) | KDM4EDHODHKDM5AKDM5BKDM4A | |
| SCHEMBL4433221 | 0.77 | MTNR1A (0.49) | KDM4EALDH1A1GLAMTNR1AMTNR1B | |
| SCHEMBL27285942 | 0.73 | KDM5A (0.49) | DHODHKDM5AKDM5BKEAP1MTNR1A | |
| SCHEMBL7648523 | 0.72 | KDM5B (0.60) | KDM4EDHODHKDM5AKDM5BKDM4A | |
| SCHEMBL13491530 | 0.72 | DHODH (0.54) | KDM4EALDH1A1DHODHKDM5AKDM5B | |
| SCHEMBL10990305 | 0.71 | KDM5A (0.47) | DHODHKDM5AKDM5B | |
| SCHEMBL10981682 | 0.71 | KDM5A (0.47) | DHODHKDM5AKDM5B | |
| SCHEMBL10982575 | 0.71 | KDM5A (0.47) | DHODHKDM5AKDM5B | |
| SCHEMBL2078975 | 0.70 | DHODH (0.58) | KDM4EALDH1A1DHODHKEAP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |