SCHEMBL4434266

SCHEMBL4434266

C1=CC2CCC1C2.CCCCCCCCC(C)COC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.40
ACE2 Q9BYF1 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
PRKCA P17252 2/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
PLA2G2C Q5R387 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27761768 0.84 ACE2 (0.52) FAAHACE2ZDHHC7ALDH1A1MAPT
SCHEMBL16556659 0.84 ACE2 (0.52) FAAHACE2ZDHHC7ALDH1A1MAPT
SCHEMBL28323464 0.84 ACE2 (0.52) FAAHACE2ZDHHC7ALDH1A1MAPT
SCHEMBL4585164 0.84 ACE2 (0.52) FAAHACE2ZDHHC7ALDH1A1MAPT
SCHEMBL27257661 0.84 ACE2 (0.52) FAAHACE2ZDHHC7ALDH1A1MAPT
SCHEMBL14525664 0.82 FAAH (0.49) FAAHACE2ZDHHC7ALDH1A1MAPT
SCHEMBL2853552 0.78 MAPT (0.57) ACE2ALDH1A1MAPT
SCHEMBL11821362 0.77 ALDH1A1 (0.50) FAAHACE2ALDH1A1MAPTPRKCA
SCHEMBL1476651 0.76 ACE2 (0.56) FAAHACE2MAPT
SCHEMBL1477205 0.76 ACE2 (0.56) FAAHACE2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1913008-B1 Cyclic olefin polymerisation process LG CHEMICAL LTD (KR) 2015-04-01 EP disclosed
US-7638653-B2 Method of preparing phosphonium compound for cyclic olefin polymerization LG CHEM, LTD. (KR) 2009-12-29 US disclosed
EP-1913008-A1 METHOD OF PREPARING PHOSPHONIUM COMPOUND FOR CYCLIC OLEFIN POLYMERIZATION LG Chem, Ltd. (KR) 2008-04-23 EP disclosed
US-20070027277-A1 Method of preparing phosphonium compound for cyclic olefin polymerization LG CHEM, LTD (PROSECUTION) (KR) 2007-02-01 US disclosed
WO-2007013759-A1 METHOD OF PREPARING PHOSPHONIUM COMPOUND FOR CYCLIC OLEFIN POLYMERIZATION LG CHEM, LTD. (KR) 2007-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027277-A1 Method of preparing phosphonium compound for cyclic olefin polymerization OXSR1, POLR2A, POLR2B FAAH 2257/4885ACE2 4431/4885ZDHHC7 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.