SCHEMBL4436159

SCHEMBL4436159

O=C(O)Oc1ccc(-c2cccc(OC(=O)O)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
RXRA P19793 2/20 0.54
RXRB P28702 2/20 0.54
EPHX1 P07099 1/20 0.49
FABP7 O15540 1/20 0.49
FABP3 P05413 1/20 0.49
FABP5 Q01469 1/20 0.49
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4260925 0.92 EPHX1 (0.55) MAPTTDP1RXRARXRBEPHX1
SCHEMBL3944512 0.92 RXRA (0.51) RXRARXRBEPHX1FABP7FABP3
SCHEMBL8678710 0.90 ABL1 (0.59) LMNAGAAMAPTTDP1RXRA
SCHEMBL4607313 0.87 LMNA (0.71) LMNAGAAMAPTTDP1RXRA
SCHEMBL686623 0.86 MEN1 (0.50) RXRARXRBEPHX1FABP7FABP3
SCHEMBL2760661 0.86 KMT2A (0.55) LMNAGAAMAPTTDP1FABP7
SCHEMBL17714039 0.86 KMT2A (0.55) LMNAGAAMAPTTDP1FABP7
SCHEMBL6207157 0.84 MAOA (0.57) LMNAGAAMAPTTDP1FABP7
SCHEMBL6223303 0.84 LMNA (0.54) LMNAGAAMAPTTDP1RXRA
Biphenyl SCHEMBL6667027 0.84 KMT2A (0.53) LMNAGAAMAPTTDP1FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-B1 POLYARYLATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2009-08-26 EP claimed
EP-0465040-B1 Polyester polymer products ICI PLC (GB) 1997-01-15 EP claimed
EP-0567998-A1 Process for the preparation of spinnable meta-aramides HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-03 EP claimed
EP-0464351-A2 Polycarbonate, polyestercarbonate and polyester moulding compositions with high melt flow BAYER AG (DE) 1992-01-08 EP claimed
EP-0444295-A1 Low-viscosity polyamide mouldings BAYER AG (DE) 1991-09-04 EP claimed
EP-0444292-A2 Easy fluoring polyamide moulding compositions BAYER AG (DE) 1991-09-04 EP claimed
EP-0398052-A2 Low-viscosity polyarylene sulfide mouldings BAYER AG (DE) 1990-11-22 EP claimed
EP-0359037-A2 Low-viscosity polyamide mouldings and mixtures BAYER AG (DE) 1990-03-21 EP claimed
EP-0595082-B1 Thermoplastically processable thermotropic moulding composition BAYER AG (DE) 1999-05-06 EP disclosed
EP-0553756-B1 Aromatic copolyamides, process for their preparation and molded articles therefrom HOECHST AG (DE) 1998-08-26 EP disclosed
EP-0499230-B1 Aromatic copolyamides, process for their preparation and shaped articles prepared from the same HOECHST AG (DE) 1996-07-24 EP disclosed
EP-0522418-B1 Aromatic copolyamides, process for their preparation and shaped articles thereof HOECHST AG (DE) 1995-11-15 EP disclosed
EP-0432561-B1 Graft cocondensate made of a polyarylenesulfide backbone and side chains with liquid crystal properties BAYER AG (DE) 1995-06-07 EP disclosed
EP-0496318-B1 Aromatic copolyamids, method of preparation and shaped articles thereof HOECHST AG (DE) 1995-04-05 EP disclosed
EP-0330037-A1 Thermoplastic block copolymers comprising blocks of carboxyl groups containing polypropylene and blocks of completely aromatic polyesters, polyestercarbonates or polyesteramides. BAYER AG (DE) 1989-08-30 EP disclosed
EP-0303935-A2 Thermotropic, aromatic polyestercarbonates, a process for their fabrication and their use BAYER AG (DE) 1989-02-22 EP disclosed
EP-0297353-A2 Moulding compositions from polycarbonate, thermotropic polymer, graft polymer and fluorinated polyolefin BAYER AG (DE) 1989-01-04 EP disclosed
EP-0141320-B1 THERMOTROPIC AROMATIC POLYESTERS WITH HIGH STIFFNESS, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FIBRES AND FILMS BAYER AG (DE) 1987-10-07 EP disclosed
EP-0236837-A2 Mixtures of polycarbonate polysiloxane block cocondensates and thermotropic polymers, process for preparing them and their use in making mouldings, filaments, fibres and foils BAYER AG (DE) 1987-09-16 EP disclosed
EP-0141320-A2 Thermotropic aromatic polyesters with high stiffness, process for their production and their use in the production of moulded articles, filaments, fibres and films BAYER AG (DE) 1985-05-15 EP disclosed