Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289075 | 0.80 | DRD2 (0.53) | NOTUMACEDRD2DRD4 | |
| SCHEMBL7554164 | 0.80 | DRD2 (0.53) | NOTUMACEDRD2DRD4 | |
| SCHEMBL30681441 | 0.80 | DRD2 (0.53) | NOTUMACEDRD2DRD4 | |
| SCHEMBL7993369 | 0.79 | DRD2 (0.54) | NOTUMACEDRD2DRD4 | |
| SCHEMBL4386325 | 0.78 | NOTUM (0.44) | NOTUMACE | |
| SCHEMBL23535880 | 0.77 | OPRM1 (0.44) | ACE | |
| SCHEMBL30681525 | 0.75 | NOTUM (0.48) | NOTUMACE | |
| SCHEMBL9930255 | 0.74 | NOTUM (0.43) | NOTUMACE | |
| SCHEMBL30681248 | 0.74 | DRD2 (0.45) | NOTUMDRD2DRD4 | |
| SCHEMBL23113116 | 0.73 | NOTUM (0.51) | NOTUMACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |