Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGLRA1GLRBKCNK10KCNK18KCNK2KCNK3KCNK9
The experimentally established mechanism targets of Halothane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Halothane SCHEMBL337605 | 1.00 | — | — | |
| Halothane SCHEMBL25588 | 1.00 | — | — | |
| Halothane SCHEMBL1612295 | 1.00 | HSD17B10 (1.00) | — | |
| Halothane SCHEMBL1295253 | 0.96 | — | — | |
| Halothane SCHEMBL5961792 | 0.96 | HSD17B10 (0.92) | — | |
| Halothane SCHEMBL15475924 | 0.92 | — | — | |
| Halothane SCHEMBL6289622 | 0.92 | — | — | |
| Halothane SCHEMBL8902191 | 0.89 | HSD17B10 (0.79) | — | |
| Halothane SCHEMBL10725043 | 0.89 | — | — | |
| Halothane SCHEMBL9138026 | 0.80 | ALDH1A1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 849 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157407-B1 | INHALER DEVICE FOR INHALABLE LIQUIDS | MEDICAL DEVELOPMENTS INTERNATIONAL LTD (AU) | 2026-03-25 | — | — | EP | claimed |
| CN-114550818-B | Evaluation method of gene sequencing mixed signal | 赛纳生物科技(北京)有限公司 | 2025-04-15 | — | — | CN | claimed |
| EP-3863708-B1 | MIXED IONIC CONDUCTORS AND CORRESPONDING DEVICES, SYSTEMS AND METHODS OF MAKING | BATTELLE MEMORIAL INSTITUTE (US) | 2024-09-11 | — | — | EP | claimed |
| CN-117202919-A | Compositions and methods for inhibiting pathogenic organisms | 韦丹塔生物科学股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| EP-3393462-B1 | COMPOSITIONS AND METHODS FOR TREATMENT, AMELIORATION, AND PREVENTION OF ANESTHESIA-INDUCED HYPOTHERMIA | UNIV ARIZONA (US) | 2023-02-01 | — | — | EP | claimed |
| EP-3337456-B1 | LIPOSOMES WITH GINSENOSIDE AS MEMBRANE MATERIAL AND PREPARATIONS AND USE THEREOF | SHANGHAI GINPOSOME PHARMATECH CO LTD (CN) | 2022-10-26 | — | — | EP | claimed |
| EP-3416688-B1 | APELIN FOR USE IN THE TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION | INST NAT SANTE RECH MED (FR) | 2022-08-17 | — | — | EP | claimed |
| CN-113266369-B | Detection device applied to ultra-long distance shield axis positioning | 上海市基础工程集团有限公司 | 2022-06-24 | — | — | CN | claimed |
| EP-3326677-B1 | INHALABLE MICROEMULSION COMPRISING ANAESTHETIC | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2022-06-22 | — | — | EP | claimed |
| EP-3230266-B1 | ADSORPTION OF FLUORINATED ANESTHETICS WITHIN THE PORES OF MOLECULAR CRYSTALS | UNIV HOUSTON SYSTEM (US) | 2022-03-02 | — | — | EP | claimed |
| EP-0680259-B1 | DEVICE FOR STUNNING OF POULTRY | STORK PMT (NL) | 1997-08-27 | — | — | EP | claimed |
| EP-0535567-B1 | Liposomes containing volatile inhalation anaesthetics, their preparation and their use | BRAUN MELSUNGEN AG (DE) | 1995-08-30 | — | — | EP | claimed |
| EP-0307625-B1 | Optical gas analyzer | GAMBRO ENGSTROM AB (SE) | 1994-04-20 | — | — | EP | claimed |
| EP-0535567-A1 | Liposomes containing volatile inhalation anaesthetics, their preparation and their use | B. Braun Melsungen AG (DE) | 1993-04-07 | — | — | EP | claimed |
| EP-0338971-B1 | PROCESS FOR PREPARING LIPOSOMES AND/OR BIOLOGICAL CELLS CONTAINING INGREDIENTS, AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-01-20 | — | — | EP | claimed |
| EP-0253777-B1 | Use of L-carnitine for the manufacture of a medicament for the treatment of toxic effects induced by the inhalation of halothane and other halogen-containing general anesthetics. | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-03-11 | — | — | EP | claimed |
| EP-0338971-A1 | Process for preparing liposomes and/or biological cells containing ingredients, and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | claimed |
| WO-1989009593-A1 | PROCESS FOR PRODUCING LIPOSOMES AND/OR BILOLOGICAL CELLS, WHICH HAVE INCLUDED INGREDIENT SUBSTANCES, AND THEIR USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1989-10-19 | — | — | WO | claimed |
| EP-0221488-A2 | Method for fighting ektoparasites | VARROTEX GMBH & CO. KG (DE) | 1987-05-13 | — | — | EP | claimed |
| EP-0027005-B1 | A METHOD OF ELECTROCHEMICAL SENSING AND A SENSOR FOR OXYGEN, HALOTHANE AND NITROUS OXIDE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-15 | — | — | EP | claimed |