Phenol

Phenol

SCHEMBL4437500

C1=CC([Zr+2]C2C=Cc3ccccc32)c2ccccc21.[O-]c1ccccc1.[O-]c1ccccc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.37
SIGMAR1 Q99720 4/20 0.34
HTR2A P28223 1/20 0.33
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL3709891 0.96 HTR6 (0.35) HTR6SIGMAR1HTR2A
SCHEMBL31357303 0.88 HTR2A (0.40) HTR6SIGMAR1HTR2ABRD4CCL2
Fluoride Ion SCHEMBL1130379 0.86 HTR2A (0.39) HTR6SIGMAR1HTR2ABRD4CCL2
Hydrochloric Acid SCHEMBL137960 0.86 HTR2A (0.39) HTR6SIGMAR1HTR2ABRD4CCL2
Hydrochloric Acid SCHEMBL29424565 0.86 HTR2A (0.39) HTR6SIGMAR1HTR2ABRD4CCL2
Bromide SCHEMBL615606 0.86 HTR2A (0.43) HTR6SIGMAR1HTR2ABRD4CCL2
SCHEMBL3838138 0.86 HTR2A (0.39) HTR6SIGMAR1HTR2ABRD4CCL2
Hydrochloric Acid SCHEMBL820052 0.84 HTR2A (0.38) HTR6SIGMAR1HTR2ABRD4CCL2
Hydrochloric Acid SCHEMBL30533388 0.84 HTR2A (0.38) HTR6SIGMAR1HTR2ABRD4CCL2
Ethylene SCHEMBL6910508 0.83 BRD4 (0.35) HTR6SIGMAR1HTR2ABRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125846-A2 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES Chemtura Organometallics GmbH (DE) 2009-12-02 EP claimed
WO-2008104382-A2 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES CHEMTURA ORGANOMETALLICS GMBH (DE) 2008-09-04 WO claimed
US-8383848-B2 Transition metal compound and catalyst for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-26 US disclosed
US-20110319578-A1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319578-A1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION AP1M1, SOD1, YAP1 HTR6 4382/4885SIGMAR1 3258/4885HTR2A 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.