Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446622 | 0.92 | ESR2 (0.47) | ESR2PSMB5LMNASMN1; SMN2MCOLN3 | |
| SCHEMBL448143 | 0.73 | CA2 (0.43) | LMNACYP2A6ALDH1A1TSHRCA1 | |
| SCHEMBL431299 | 0.72 | MGLL (0.48) | ESR2SMN1; SMN2ALOX5MGLLALDH1A1 | |
| SCHEMBL28382574 | 0.71 | RXRA (0.40) | BACE1MGLLALDH1A1CA1CA2 | |
| SCHEMBL30255125 | 0.71 | PDCD1 (0.44) | ESR2SMN1; SMN2BACE1MGLLCYP2A6 | |
| SCHEMBL8986922 | 0.69 | ESR2 (0.52) | ESR2PSMB5LMNASMN1; SMN2MCOLN3 | |
| SCHEMBL24665564 | 0.68 | MGLL (0.48) | ESR2LMNASMN1; SMN2BACE1ALOX5 | |
| SCHEMBL9423370 | 0.68 | PSMB5 (0.49) | ESR2PSMB5LMNASMN1; SMN2MCOLN3 | |
| SCHEMBL19464511 | 0.67 | HDAC7 (0.49) | ESR2PSMB5LMNAMETAP2HDAC7 | |
| Water SCHEMBL19349803 | 0.66 | PSMB5 (0.47) | ESR2PSMB5LMNASMN1; SMN2MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121584-A2 | NOVEL HERBICIDES | Syngeta Participations AG (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110308-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |