Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL3319065 | 0.91 | FFAR3 (0.33) | LDHASRRGABRPGABRDGABRA1 | |
| SCHEMBL27477349 | 0.80 | GABRP (0.39) | LDHASRRGABRPGABRDGABRA1 | |
| SCHEMBL1162348 | 0.77 | LMNA (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3415362 | 0.76 | LDHA (0.42) | LDHASRRTSHR | |
| SCHEMBL242500 | 0.74 | TSHR (0.47) | LDHASRRTSHR | |
| SCHEMBL7463374 | 0.74 | LDHA (0.40) | LDHASRRTSHR | |
| SCHEMBL26939174 | 0.74 | LDHA (0.40) | LDHASRRTSHR | |
| SCHEMBL5349565 | 0.72 | LDHA (0.38) | LDHASRRGABRPGABRDGABRA1 | |
| SCHEMBL22124620 | 0.72 | MAPT (0.45) | LDHASRROR51E2 | |
| SCHEMBL5793622 | 0.70 | LDHA (0.36) | LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702194-A | Anti-viral compounds | ABBOTT LAB | 2012-10-03 | — | — | CN | disclosed |
| CN-102702193-A | Anti-viral compounds | ABBOTT LAB | 2012-10-03 | — | — | CN | disclosed |
| EP-2134345-A2 | TRIAZOLQUINOLONIC DERIVATIVES WITH ANTIMYCOBACTERIAL ACTIVITY | Need Pharmaceuticals S.r.l. (IT) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008107781-A2 | TRIAZOLQUINOLONIC DERIVATIVES WITH ANTIMYCOBACTERIAL ACTIVITY | NEED PHARMACEUTICALS S.R.L. (IT) | 2008-09-12 | — | — | WO | disclosed |
| US-6861438-B2 | Antiviral agents | PFIZER (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1467999-A1 | OXOTHIENO[3,2-B]PYRIDINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-10-20 | — | — | EP | disclosed |
| US-20040138449-A1 | Antiviral agents | PHARMACIA & UPJOHN COMPANY | 2004-07-15 | — | — | US | disclosed |
| WO-2003059912-A1 | OXOTHIENO (3, 2-B) PYRIDINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | disclosed |
| EP-0134165-B1 | 7-(PYRROL-1-YL)-1-ETHYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID AND 7-(PYRROL-1-YL)-1-ETHYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | PROVESAN S.A. (CH) | 1988-06-08 | — | — | EP | disclosed |
| EP-0134165-A2 | 7-(Pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments | PROVESAN S.A. (CH) | 1985-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138449-A1 | Antiviral agents | IRF3, IFNAR1, EIF2AK2 | LDHA 2308/4885SRR 822/4885GABRP 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.