Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349553 | 0.87 | MGAM (0.46) | TP53MGAMGAASIMGAM2 | |
| SCHEMBL242500 | 0.82 | TSHR (0.47) | LDHASRRTSHRMMP1MMP2 | |
| SCHEMBL11453250 | 0.80 | MGAM (0.52) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3415362 | 0.79 | LDHA (0.42) | LDHASRRTSHRSLC22A6 | |
| SCHEMBL11205973 | 0.78 | CYP19A1 (0.38) | LDHASRRTSHRMMP1MMP2 | |
| SCHEMBL5859547 | 0.78 | MMP1 (0.38) | LDHASRRTSHRMMP1MMP2 | |
| SCHEMBL9065300 | 0.78 | LDHA (0.36) | LDHASRRTSHRMMP1MMP2 | |
| Benzene SCHEMBL28101101 | 0.78 | TSHR (0.53) | LDHASRRGAATSHRALDH1A1 | |
| SCHEMBL27477349 | 0.78 | GABRP (0.39) | LDHASRRTSHRMMP1MMP2 | |
| SCHEMBL902897 | 0.78 | EGLN1 (0.46) | TSHRLMNAGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250180-B2 | Anti-prostate cancer composition and therapeutic uses therefor | SINHUE LLC | 2007-07-31 | — | — | US | disclosed |
| US-20050147701-A1 | Anti-prostate cancer composition and therapeutic uses therefor | SINHUE LLC | 2005-07-07 | — | — | US | disclosed |