SCHEMBL4438634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4432757	0.91	HTT (0.71)	HTTSMN1; SMN2ALDH1A1HPGDTDP1
	SCHEMBL4437408	0.91	NAMPT (0.55)	HTTSMN1; SMN2ALDH1A1HPGDNAMPT
	SCHEMBL4430623	0.90	ALDH1A1 (0.53)	HTTALDH1A1HPGDNAMPTKDM4E
	SCHEMBL4430576	0.90	HTT (0.66)	HTTSMN1; SMN2ALDH1A1HPGDTDP1
	SCHEMBL14080700	0.89	ENPP2 (0.47)	HTTSMN1; SMN2ALDH1A1HPGDNAMPT
	SCHEMBL4437330	0.89	L3MBTL1 (0.59)	HTTALDH1A1NAMPTKDM4ECACNA1H
	SCHEMBL4429355	0.87	MEN1 (0.51)	SMN1; SMN2ALDH1A1HPGDNAMPTKDM4E
	SCHEMBL4523572	0.86	MGLL (0.47)	HTTNAMPTCACNA1HL3MBTL1L3MBTL3
	SCHEMBL4518846	0.86	PDE4B (0.59)	ALDH1A1HPGDKDM4EPOLBHRH3
	SCHEMBL4529122	0.86	L3MBTL3 (0.51)	HTTALDH1A1NAMPTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.