SCHEMBL4608929

SCHEMBL4608929

Cc1[c]cccc1-c1cc(Cl)ccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
HPGD P15428 1/20 0.37
NTSR1 P30989 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SAE1 Q9UBE0 1/20 0.37
UBA2 Q9UBT2 1/20 0.37
HTR2B P41595 1/20 0.36
PDE4D Q08499 1/20 0.36
TP53 P04637 1/20 0.35
S100A4 P26447 1/20 0.35
PTPN11 Q06124 1/20 0.34
IDO1 P14902 1/20 0.34
PDE2A O00408 4/20 0.34
PDE10A Q9Y233 3/20 0.34
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4431124 0.86 ELANE (0.36) ALDH1A1MAPTMEN1HPGDKMT2A
SCHEMBL4430967 0.86 IDO1 (0.39) ALDH1A1HPGDS100A4IDO1PDE2A
SCHEMBL4428493 0.83 GABRA1 (0.34) ALDH1A1MAPTKMT2APDE2APDE10A
SCHEMBL15637039 0.81 PTPN1 (0.40) PTPN1ALDH1A1MAPTMEN1HPGD
SCHEMBL6852286 0.81 KMT2A (0.43) ALDH1A1MAPTHPGDKMT2ATP53
SCHEMBL4439261 0.79 HSD11B1 (0.42) PDE2APDE10A
SCHEMBL15637150 0.79 PTPN1 (0.38) PTPN1ALDH1A1MAPTMEN1HPGD
SCHEMBL17514517 0.78 PTPN1 (0.36) PTPN1ALDH1A1MAPTMEN1HPGD
SCHEMBL22115865 0.78
SCHEMBL6823830 0.76 PTGS2 (0.42) ALDH1A1MEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008091594-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
EP-1948649-A2 FUNGICIDAL CARBOXAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-30 EP disclosed
WO-2007014290-A2 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-01 WO disclosed