Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432361 | 0.84 | ALDH1A1 (0.33) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL4553496 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4439277 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPK1RAPGEF4 | |
| SCHEMBL4440097 | 0.76 | IDO1 (0.39) | L3MBTL1KDM4ERAPGEF4 | |
| SCHEMBL10531354 | 0.74 | CNR1 (0.35) | ALDH1A1NPC1MAPTMAPK1RAB9A | |
| SCHEMBL4430076 | 0.73 | ALDH1A1 (0.35) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL3912578 | 0.73 | NPC1 (0.35) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL4439151 | 0.72 | NOTUM (0.43) | CYP1A2RAPGEF4 | |
| Chamazulene SCHEMBL180449 | 0.72 | LMNA (0.50) | ALDH1A1NPC1LMNAMAPTMAPK1 | |
| Chamazulene SCHEMBL29562128 | 0.72 | LMNA (0.50) | ALDH1A1NPC1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |