SCHEMBL4440202

SCHEMBL4440202

CCCC[C@@H](N=C=O)N=C=S

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.35
TRPV1 Q8NER1 2/20 0.35
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4621487 1.00 TRPA1 (0.35) TRPA1TRPV1NAAA
SCHEMBL108629 0.89 DNM1 (0.35)
Methane SCHEMBL9127523 0.87 DNM1 (0.33)
SCHEMBL112561 0.83 MAPT (0.39)
SCHEMBL483526 0.83 NAAA (0.43) TRPA1TRPV1NAAA
SCHEMBL6577575 0.81 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL6436761 0.81 MAPT (0.42)
SCHEMBL7133116 0.81 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL8743022 0.81 MAPT (0.42)
SCHEMBL362511 0.81 MAPT (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009151942-A2 REINFORCED POLYMER FOAMS, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME SEMMES, INC. (US) 2009-12-17 WO disclosed