SCHEMBL4621487

SCHEMBL4621487

CCCCC(N=C=O)N=C=S

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.35
TRPV1 Q8NER1 2/20 0.35
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4440202 1.00 TRPA1 (0.35) TRPA1TRPV1NAAA
SCHEMBL108629 0.89 DNM1 (0.35)
Methane SCHEMBL9127523 0.87 DNM1 (0.33)
SCHEMBL112561 0.83 MAPT (0.39)
SCHEMBL483526 0.83 NAAA (0.43) TRPA1TRPV1NAAA
SCHEMBL6577575 0.81 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL6436761 0.81 MAPT (0.42)
SCHEMBL7133116 0.81 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL8743022 0.81 MAPT (0.42)
SCHEMBL362511 0.81 MAPT (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951173-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2018-04-24 US disclosed
US-20160215087-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2016-07-28 US disclosed
EP-1885763-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG Industries Ohio, Inc. (US) 2008-02-13 EP disclosed
WO-2006130339-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG INDUSTRIES OHIO, INC. (US) 2006-12-07 WO disclosed
EP-1448651-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG Industries Ohio, Inc. (US) 2004-08-25 EP disclosed
WO-2004011506-A1 A HIGH REFRACTIVE INDEX POLYMERIZABLE COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2004-02-05 WO disclosed
WO-2003044070-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG INDUSTRIES OHIO, INC. (US) 2003-05-30 WO disclosed
EP-1265938-A1 OPTICAL RESIN COMPOSITION PPG Industries Ohio, Inc. (US) 2002-12-18 EP disclosed
EP-1250370-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
EP-1250369-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
WO-2001036506-A1 OPTICAL RESIN COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036507-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036508-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-1999020668-A1 HIGH REFRACTIVE INDEX OPHTHALMIC MATERIALS TECHNOLOGY RESOURCE INTERNATIONAL CORPORATION (US) 1999-04-29 WO disclosed