Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690304 | 0.73 | ALDH1A1 (0.45) | L3MBTL1TSHRSMN1; SMN2CA1CA2 | |
| SCHEMBL15761490 | 0.71 | ENPP2 (0.41) | ENPP2TSHRCA1CA2LIPG | |
| SCHEMBL21270 | 0.71 | GABRA1 (0.54) | ENPP2TSHRCA1CA2LIPG | |
| SCHEMBL29430856 | 0.71 | GABRA1 (0.54) | ENPP2TSHRCA1CA2LIPG | |
| SCHEMBL2247879 | 0.69 | ENPP2 (0.43) | ENPP2TSHRCA1CA2LIPG | |
| SCHEMBL3762332 | 0.68 | ENPP2 (0.52) | ENPP2TSHRCA1CA2LIPG | |
| SCHEMBL2558207 | 0.68 | GABBR2 (0.40) | TSHRSMN1; SMN2 | |
| SCHEMBL2360079 | 0.67 | DPP4 (0.46) | — | |
| SCHEMBL29951757 | 0.67 | ENPP2 (0.41) | ENPP2TSHRCA1CA2LIPG | |
| SCHEMBL29468969 | 0.67 | ENPP2 (0.41) | ENPP2TSHRCA1CA2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120579-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBOTT LABORATORIES (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083027-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBOTT LABORATORIES (US) | 2008-07-10 | — | — | WO | disclosed |