SCHEMBL4441405

SCHEMBL4441405

CCOC(=O)C1CC=C(Cl)CC1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ KMT2A Q03164 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KDM4E B2RXH2 4/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ MAPT P10636 2/20 0.41
▸ HSD11B1 P28845 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ POLB P06746 1/20 0.40
▸ PDK1 Q15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431486 0.83 LMNA (0.51) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL31601392 0.83 LMNA (0.51) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL12519547 0.82 ALOX15 (0.49) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL10684675 0.81 SMN1; SMN2 (0.39) TSHRKMT2AMEN1KDM4EALDH1A1
SCHEMBL23091547 0.81 TSHR (0.48) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL2122977 0.81 TSHR (0.48) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL20562726 0.81 ALOX15 (0.57) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL11337020 0.81 TSHR (0.48) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL11340760 0.79 TSHR (0.58) TSHRALOX15MAPK1KMT2AMEN1
SCHEMBL22223246 0.79 ALOX15 (0.47) TSHRALOX15MAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364938-B1 PROCESS FOR PRODUCING FLUORINE COMPOUND ASAHI GLASS CO LTD (JP) 2009-05-13 — — EP disclosed
CN-1231453-C Process for producing fluorine-containing compound ASAHI GLASS CO LTD (JP) 2005-12-14 — — CN disclosed
US-6903230-B2 Process for producing a fluorine-containing compound ASAHI GLASS COMPANY, LIMITED (JP) 2005-06-07 — — US disclosed
CN-1489572-A Process for producing fluorine-containing compound ������������ʽ���� 2004-04-14 — — CN disclosed
US-20040024269-A1 Process for producing a fluorine-containing compound ASAHI GLASS COMPANY LIMITED (JP) 2004-02-05 — — US disclosed
EP-1364938-A1 PROCESS FOR PRODUCING FLUORINE COMPOUND Asahi Glass Company, Limited (JP) 2003-11-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024269-A1 Process for producing a fluorine-containing compound FOXO1, PFAS, PFKFB2 TSHR 635/4885ALOX15 1293/4885MAPK1 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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