Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927016 | 0.86 | ALDH1A1 (0.69) | NPC1ALDH1A1GLAHTTRAB9A | |
| Carbamic Acid SCHEMBL6468271 | 0.85 | NPC1 (0.62) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL1259310 | 0.83 | PDK1 (0.58) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL3156630 | 0.82 | NPC1 (0.53) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL8940199 | 0.82 | ALDH1A1 (0.44) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL5907003 | 0.81 | ALDH1A1 (0.54) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL29280746 | 0.81 | ALDH1A1 (0.52) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL3153139 | 0.81 | NPC1 (0.51) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL3716240 | 0.80 | L3MBTL1 (0.47) | ALDH1A1SMN1; SMN2TSHRPDK1MEN1 | |
| SCHEMBL3157765 | 0.80 | NPC1 (0.50) | NPC1ALDH1A1GLAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114874-A2 | METHOD FOR PREPARING FLUORINATED SULPHANYLAMIDES AND SULPHINAMIDINES AND USES THEREOF | Aventis Pharma S.A. (FR) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008110698-A2 | METHOD FOR PREPARING FLUORINATED SULPHANYLAMIDES AND SULPHINAMIDINES AND USES THEREOF | AVENTIS PHARMA S.A. (FR) | 2008-09-18 | — | — | WO | disclosed |