SCHEMBL444363

SCHEMBL444363

CC1(C)CC(N=C=S)CC(C)(C)N1O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APLNR P35414 3/20 0.41
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441906 0.79 ALDH1A1 (0.42) GAAL3MBTL1
SCHEMBL444362 0.79 APLNR (0.41) APLNR
SCHEMBL20313799 0.76 APLNR (0.38) APLNR
SCHEMBL13164372 0.71 GAA (0.43) GAAL3MBTL1
SCHEMBL24849809 0.70 GAA (0.41) GAAL3MBTL1
SCHEMBL28703350 0.70 APLNR (0.50) APLNR
SCHEMBL20323315 0.67 APLNR (0.38) APLNR
SCHEMBL6259406 0.66 GAA (0.42) GAAL3MBTL1
SCHEMBL18226691 0.66
Tempol Hydroxylamine SCHEMBL23902 0.64 GAA (0.56) GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12110271-B2 Manufacturing method for 4-methoxypyrrole derivatives DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2024-10-08 US claimed
WO-2023229323-A1 METHOD FOR PREPARING 6-METHOXYPYRIDIN-3-YL DERIVATIVE 일동제약(주) 2023-11-30 WO claimed
CN-115710701-A Chemical gold plating solution and application 广东东硕科技有限公司 2023-02-24 CN claimed
WO-2022264971-A1 METHOD FOR EVALUATING QUALITY OF SPERM 国立大学法人東海国立大学機構 2022-12-22 WO claimed
WO-2022251679-A1 NITROXIDE RADICALS FOR USE AS ANTIVIRAL TREATMENT FOR CORONAVIRUS INFECTION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-12-01 WO claimed
CN-115108969-A Efficient and migration-resistant antioxidant as well as preparation method and application thereof 华南理工大学 2022-09-27 CN claimed
EP-3854784-A1 METHOD FOR PRODUCING 4-METHOXY PYRROLE DERIVATIVE Daewoong Pharmaceutical Co., Ltd. (KR) 2021-07-28 EP claimed
US-20210221770-A1 MANUFACTURING METHOD FOR 4-METHOXYPYRROLE DERIVATIVES DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2021-07-22 US claimed
WO-2020060213-A1 METHOD FOR PRODUCING 4-METHOXY PYRROLE DERIVATIVE 주식회사 대웅제약 2020-03-26 WO claimed
US-10245256-B2 Nitroxides for use in treating or preventing diabetes and obesity MITOS PHARMACEUTICALS, INC. (US) 2019-04-02 US claimed
US-20150359782-A1 NITROXIDES FOR USE IN TREATING OR PREVENTING DIABETES AND OBESITY Knobbe, Martens, Olson & Bear, LLP 2015-12-17 US claimed
US-9101619-B2 Nitroxides for use in treating or preventing diabetes and obesity MITOS PHARMACEUTICALS, INC. (US) 2015-08-11 US claimed
US-20140356540-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2014-12-04 US claimed
EP-2655527-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS ALLNEX AUSTRIA GmbH (AT) 2013-10-30 EP claimed
WO-2012085016-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2012-06-28 WO claimed
US-8138268-B2 Adhesive composition, circuit connecting material, connecting structure for circuit member, and semiconductor device HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-03-20 US claimed
EP-0983334-A1 ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION Call, Krimhild (DE) 2000-03-08 EP claimed
WO-1999001607-A2 ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS CALL, KRIMHILD (DE) 1999-01-14 WO claimed
WO-1998055684-A1 MULTI-COMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, MATERIALS CONTAINING LIGNIN OR SIMILAR SUBSTANCES AND METHODS FOR PRODUCING THE SAME Consortium für elektrochemische Industrie GmbH (DE) 1998-12-10 WO claimed
WO-1998051772-A1 ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION CALL, KRIMHILD (DE) 1998-11-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150359782-A1 NITROXIDES FOR USE IN TREATING OR PREVENTING DIABETES AND OBESITY TXNRD2, TXN2, TET1 APLNR 2866/4885GAA 2772/4885L3MBTL1 850/4885
US-20210221770-A1 MANUFACTURING METHOD FOR 4-METHOXYPYRROLE DERIVATIVES COMT, TH, HPD APLNR 4804/4885GAA 1321/4885L3MBTL1 941/4885
US-10245256-B2 Nitroxides for use in treating or preventing diabetes and obesity TXNRD2, TXN2, TET1 APLNR 2866/4885GAA 2772/4885L3MBTL1 850/4885
US-12110271-B2 Manufacturing method for 4-methoxypyrrole derivatives COMT, TH, HPD APLNR 4804/4885GAA 1321/4885L3MBTL1 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.