Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375511 | 0.81 | SIGMAR1 (0.65) | DPP7CYP2D6HRH1DRD2HTR1A | |
| SCHEMBL4443786 | 0.80 | HTR7 (0.61) | HRH1HRH3DRD2HTR1AHRH2 | |
| SCHEMBL12261943 | 0.77 | DRD4 (0.77) | HRH1HRH3DRD2DRD4 | |
| SCHEMBL5756091 | 0.77 | DPP7 (1.00) | DPP7CYP3A4CYP2D6 | |
| SCHEMBL31232707 | 0.77 | ALDH1A1 (0.67) | DRD2HTR1A | |
| SCHEMBL39631 | 0.76 | DPP7 (0.73) | DPP7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10118660 | 0.76 | DRD2 (0.51) | HRH1HRH3DRD2HRH2 | |
| Hydrochloric Acid SCHEMBL5754930 | 0.76 | DPP7 (0.96) | DPP7CYP3A4CYP2D6 | |
| SCHEMBL8883456 | 0.76 | DPP7 (0.96) | DPP7CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL5758788 | 0.75 | DPP7 (0.71) | DPP7CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |