SCHEMBL4444470

SCHEMBL4444470

O=CCCc1ccccc1C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 6/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
TRIM24 O15164 2/20 0.41
TRIM33 Q9UPN9 2/20 0.41
TSHR P16473 1/20 0.41
GAA P10253 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
ERN1 O75460 2/20 0.34
SRC P12931 1/20 0.33
MITF O75030 1/20 0.33
CYP2A6 P11509 2/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28607303 0.84 ADH1B (0.36) LMNAKMT2AMEN1THRBBLM
SCHEMBL17006106 0.83 LMNA (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL10886670 0.83 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL2834598 0.82 MEN1 (0.39) LMNAKMT2AMEN1THRBBLM
SCHEMBL22877410 0.80 LMNA (0.43) LMNAKMT2AMEN1THRBBLM
SCHEMBL14465961 0.80 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL10579156 0.79 NFE2L2 (0.44) LMNAALDH1A1CYP2A6
SCHEMBL6753105 0.78 TDP1 (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL5302766 0.78 TAAR1 (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL547665 0.78 LMNA (0.50) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP disclosed
EP-1941798-B1 Nematicidal compositions DEVGEN NV (BE) 2012-05-23 EP disclosed
US-20090209605-A1 NEMATICIDAL COMPOSITIONS DEVGEN N.V. (BE) 2009-08-20 US disclosed
EP-1969940-A2 Nematicidal compositions Devgen NV (BE) 2008-09-17 EP disclosed
EP-1969939-A2 Nematicidal compositions Devgen NV (BE) 2008-09-17 EP disclosed
EP-1941798-A2 Nematicidal compositions Devgen NV (BE) 2008-07-09 EP disclosed
EP-1941799-A2 Nematicidal compositions Devgen NV (BE) 2008-07-09 EP disclosed
EP-1938691-A2 Nematicidal compositions Devgen NV (BE) 2008-07-02 EP disclosed
US-7393985-B2 Supported ruthenium nanoparticle catalyst for cis -dihydroxylation and oxidative cleavage of alkenes THE UNIVERSITY OF HONG KONG (CN) 2008-07-01 US disclosed
US-7393985-B2 Supported ruthenium nanoparticle catalyst for cis -dihydroxylation and oxidative cleavage of alkenes THE UNIVERSITY OF HONG KONG (CN) 2008-07-01 US disclosed
US-20080146445-A1 Nematicidal Compositions DEVGEN NV (BE) 2008-06-19 US disclosed
EP-1835807-A1 NEMATICIDAL COMPOSITIONS Devgen N.V. (BE) 2007-09-26 EP disclosed
WO-2006063848-A1 NEMATICIDAL COMPOSITIONS DEVGEN N.V. (BE) 2006-06-22 WO disclosed
US-5576009-A Microcapsulated pesticidal formulations, their preparation and use CIBA-GEIGY CORPORATION (US) 1996-11-19 US disclosed
EP-0596941-A1 ACID-SUBSTITUTED TERNARY ACETAL POLYMERS AND USE THEREOF IN PHOTOSENSITIVE COMPOSITIONS AND LITHOGRAPHIC PRINTING PLATES. EASTMAN KODAK CO (US) 1994-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209605-A1 NEMATICIDAL COMPOSITIONS ACHE, DNPH1, NANP LMNA 2018/4885KMT2A 1935/4885MEN1 4411/4885
US-20080146445-A1 Nematicidal Compositions ACHE, DNPH1, NANP LMNA 2018/4885KMT2A 1935/4885MEN1 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.