Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | SCD | O00767 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590505 | 0.84 | SCD (0.55) | CNR2SCD | |
| SCHEMBL4556505 | 0.81 | TRPM8 (0.43) | TRPM8SCD | |
| SCHEMBL4450951 | 0.79 | SCD (0.53) | TRPM8CNR2SCD | |
| SCHEMBL4557042 | 0.73 | CNR2 (0.39) | TRPM8CNR2 | |
| SCHEMBL4555897 | 0.73 | CNR2 (0.42) | TRPM8CNR2SCD | |
| SCHEMBL13770570 | 0.71 | TRPM8 (0.49) | TRPM8 | |
| SCHEMBL13930227 | 0.70 | TRPM8 (0.39) | TRPM8CNR2SCD | |
| SCHEMBL537759 | 0.68 | HTR2C (0.50) | TRPM8 | |
| SCHEMBL4566242 | 0.68 | CYP3A4 (0.42) | TRPM8SCD | |
| SCHEMBL4556319 | 0.67 | SCD (0.35) | CNR2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037542-A2 | SPIROCYCLIC COMPOUNDS AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-03-26 | — | — | WO | disclosed |