SCHEMBL4445755

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4445753	0.85	MME (0.52)	MMELAP3
	SCHEMBL3623644	0.83	MME (0.68)	MME
	SCHEMBL24572013	0.82	MMP2 (0.61)	CHRNA1CHRNGCHRNB1CHRNDMMP2
	SCHEMBL23933822	0.78	GRIA1 (0.69)	CHRNA1CHRNGCHRNB1CHRNDCHRNB2
	SCHEMBL23933818	0.78	GRIA1 (0.69)	CHRNA1CHRNGCHRNB1CHRNDCHRNB2
	SCHEMBL11805463	0.78	ACE (0.69)	MME
	SCHEMBL7098130	0.77	MME (0.53)	MMETLR2CHRNB2CHRNB4CHRNA3
	SCHEMBL7098126	0.77	MME (0.53)	MMETLR2CHRNB2CHRNB4CHRNA3
	SCHEMBL18375234	0.76	ALPI (0.59)	—
	SCHEMBL11254327	0.76	ALPI (0.59)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.