Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.85 |
| ▸ | THRB | P10828 | 1/20 | 0.85 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.48 |
| ▸ | ADH1C | P00326 | 1/20 | 0.48 |
| ▸ | ADH1A | P07327 | 1/20 | 0.48 |
| ▸ | ADH7 | P40394 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208455 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL4940619 | 0.90 | IDO1 (0.94) | IDO1THRBCA2CA1ALOX12 | |
| Bromide SCHEMBL23360794 | 0.90 | IDO1 (0.94) | IDO1THRBCA2CA1ALOX12 | |
| Hydrochloric Acid SCHEMBL359448 | 0.90 | IDO1 (0.94) | IDO1THRBCA2CA1ALOX12 | |
| Hydrochloric Acid SCHEMBL8359792 | 0.87 | IDO1 (0.90) | IDO1THRBCA2CA1ALOX12 | |
| Hydroxyamine SCHEMBL250901 | 0.87 | IDO1 (0.90) | IDO1THRBCA2CA1ALOX12 | |
| Hydrochloric Acid SCHEMBL27851954 | 0.87 | IDO1 (0.90) | IDO1THRBCA2CA1ALOX12 | |
| SCHEMBL28863273 | 0.85 | IDO1 (0.85) | IDO1THRBCA2CA1ALOX12 | |
| Succinic Acid SCHEMBL29992800 | 0.84 | THRB (0.74) | IDO1THRBMEN1KMT2AHDAC8 | |
| Propane SCHEMBL5804162 | 0.83 | IDO1 (0.81) | IDO1THRBCA2CA1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012011-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| EP-1981596-A2 | NOVEL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007082262-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012011-A1 | Novel Compounds | TRPV4, TRPV1, TRPV3 | IDO1 1289/4885THRB 1068/4885CA2 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.