Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.50 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.50 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.94 |
| ▸ | THRB | P10828 | 1/20 | 0.94 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27851954 | 0.97 | IDO1 (0.90) | IDO1THRBMAPTCYP3A4KDM4E | |
| SCHEMBL208455 | 0.97 | — | — | |
| Bromide SCHEMBL23360794 | 0.94 | IDO1 (0.94) | IDO1THRBMAPTCYP3A4KDM4E | |
| Ammonia Solution, Strong SCHEMBL4940619 | 0.94 | IDO1 (0.94) | IDO1THRBMAPTCYP3A4KDM4E | |
| Propane SCHEMBL5804162 | 0.93 | IDO1 (0.81) | IDO1THRBMAPTCYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL8359792 | 0.92 | IDO1 (0.90) | IDO1THRBMAPTCYP3A4KDM4E | |
| Hydroxyamine SCHEMBL250901 | 0.92 | IDO1 (0.90) | IDO1THRBMAPTCYP3A4KDM4E | |
| SCHEMBL28863273 | 0.90 | IDO1 (0.85) | IDO1THRBMAPTCYP3A4KDM4E | |
| Formaldehyde SCHEMBL4447100 | 0.90 | IDO1 (0.85) | IDO1THRBMAPTCYP3A4KDM4E | |
| Toluene SCHEMBL28370603 | 0.85 | IDO1 (0.77) | IDO1THRBMAPTCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260027227-A1 | NOVEL THIOL REDUCTANT, METHOD AND USE THEREOF | SUZHOU BIOREINNO BIOTECHNOLOGY LTD COMPANY (CN) | 2026-01-29 | — | — | US | claimed |
| US-20250326775-A1 | A NOVEL THIOL REDUCTANT, PREPARATION METHOD AND USE THEREOF | SUZHOU BIOREINNO BIOTECHNOLOGY LTD COMPANY (CN) | 2025-10-23 | — | — | US | claimed |
| EP-4577552-A1 | A NOVEL THIOL REDUCTANT, METHOD AND USE THEREOF | SUZHOU BIOREINNO BIOTECHNOLOGY LIMITED COMPANY (CN) | 2025-07-02 | — | — | EP | claimed |
| CN-120064257-A | Colorimetric array sensor constructed by combining hydroxylamine hydrochloride with pH indicator and application thereof | 浙江工业大学 | 2025-05-30 | — | — | CN | claimed |
| CN-116199595-B | Production method of benzyl hydroxylamine hydrochloride | 苏州诚和医药化学有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119954679-A | Preparation method of N-benzyl hydroxylamine hydrochloride | 苏州诚和医药化学有限公司 | 2025-05-09 | — | — | CN | claimed |
| EP-4536670-A1 | A NOVEL THIOL REDUCTANT, PREPARATION METHOD AND USE THEREOF | SUZHOU BIOREINNO BIOTECHNOLOGY LIMITED COMPANY (CN) | 2025-04-16 | — | — | EP | claimed |
| CN-119487044-A | Novel mercaptan reducing agent and preparation method and application thereof | 苏州佰睿壹生物技术有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119365471-A | Novel thiol reducing agents, methods and uses thereof | 苏州佰睿壹生物技术有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-116239492-B | Continuous synthesis process of N-benzyl hydroxylamine hydrochloride | 中南大学 | 2024-06-14 | — | — | CN | claimed |
| US-6660741-B2 | Coupling an O-protected methoxypyrrolidine or derivatives with N-protected amino acid 2,5-dioxo-pyrrolidinyl ester to form intermediate, deportecting with trifluoroacetic acid to form pyrrolidine-1-carbonyl-2-methylamine or derivatives | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2003-12-09 | — | — | US | claimed |
| US-20020198156-A1 | Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2002-12-26 | — | — | US | claimed |
| WO-2002074050-A2 | ASYMMETRIC SYNTHESIS OF (S, S, R)-(-)-ACTINONIN AND ITS ANALOGS AND USES THEREFOR | SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2002-09-26 | — | — | WO | claimed |
| CN-1308066-A | Preparation of chiral succinic acid derivative | HOFFMANN LA ROCHE (CH) | 2001-08-15 | — | — | CN | claimed |
| EP-0757982-B1 | Biphenylic compounds, process for their preparations and intermediates for this process, their use as 5-alpha-reductase inhibitors and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | claimed |
| US-6031103-A | Process for manufacturing 1-[3-cyclopentyl -2(R)-[1(R)-hydroxycarbamoyl)-2-(3, 4, 4-trimethyl -2, 5-D ioxo-1-imidazolidinyl) ethyl] propionyl] piperidine | HOFFMANN-LA ROCHE INC. (US) | 2000-02-29 | — | — | US | claimed |
| EP-0911324-A1 | Process for the preparation of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-04-28 | — | — | EP | claimed |
| CN-1213663-A | Process for producing chiral succinic acid derivative | HOFFMANN LA ROCHE (US) | 1999-04-14 | — | — | CN | claimed |
| CN-1177595-A | Process for preparing chiral succinic acid derivatives | HOFFMANN LA ROCHE (CH) | 1998-04-01 | — | — | CN | claimed |
| EP-0816341-A1 | Process for the preparation of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198156-A1 | Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor | HASPIN, CYTH2, ACTR3 | CA2 3386/4885GAA 4132/4885MAOA 2867/4885 |
| US-20260027227-A1 | NOVEL THIOL REDUCTANT, METHOD AND USE THEREOF | CBR1, SCLY, SSB | CA2 180/4885GAA 4792/4885MAOA 4359/4885 |
| US-20250326775-A1 | A NOVEL THIOL REDUCTANT, PREPARATION METHOD AND USE THEREOF | TMT1A, TST, PRDX3 | CA2 3908/4885GAA 3712/4885MAOA 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.