Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27411999 | 0.95 | DRD2 (0.35) | DRD2DRD4DRD3PNMTNPC1 | |
| Hydrochloric Acid SCHEMBL27425148 | 0.83 | PNMT (0.42) | DRD2DRD4DRD3PNMTNPC1 | |
| SCHEMBL27348144 | 0.83 | PNMT (0.45) | DRD2DRD4DRD3PNMTNPC1 | |
| Hydrochloric Acid SCHEMBL7913247 | 0.82 | PNMT (0.36) | DRD2DRD4DRD3PNMTNPC1 | |
| Hydrochloric Acid SCHEMBL27650656 | 0.82 | PNMT (0.36) | DRD2DRD4DRD3PNMTNPC1 | |
| SCHEMBL28220071 | 0.81 | PNMT (0.44) | DRD2DRD4DRD3PNMTNPC1 | |
| SCHEMBL28286932 | 0.81 | PNMT (0.44) | DRD2DRD4DRD3PNMTNPC1 | |
| SCHEMBL6437444 | 0.81 | PNMT (0.37) | DRD2DRD4DRD3PNMTNPC1 | |
| SCHEMBL7625230 | 0.81 | PNMT (0.37) | DRD2DRD4DRD3PNMTNPC1 | |
| SCHEMBL9659755 | 0.81 | PNMT (0.37) | DRD2DRD4DRD3PNMTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255425-B1 | EXTRUDED ARTICLE FORMED BY EXTRUSION OF SYNDIOTACTIC PROPYLENE HOMOPOLYMER HAVING SYNDIOTACTIC PENTAD FRACTION OF AT LEAST 0.7 | MITSUI CHEMICALS, INC. (JP) | 2001-07-03 | — | — | US | claimed |
| US-6218330-B1 | REACTING A METALLOCENE WITH AN ALUMOXANE; REACTING MIXTURE COMPRISING ALKYLMETALLOCENIUM WITH ANIONIC ALUMONXANE OLIGOMER WITH SUPPORT; RECOVERING SUPPORTED METALLOCENE-ALUMOXANE CATALYST AS DRY SOLID | FINA RESEARCH, S. A. (BE) | 2001-04-17 | — | — | US | claimed |
| US-5847059-A | Catalyst yield from supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 1998-12-08 | — | — | US | claimed |
| EP-0849286-A1 | Improved polymer yield from supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 1998-06-24 | — | — | EP | claimed |
| EP-0464684-B1 | Syndiotactic crystalline copolymers of propylene | SPHERILENE SRL (IT) | 1995-06-14 | — | — | EP | claimed |
| EP-0464684-A2 | Syndiotactic crystalline copolymers of propylene | SPHERILENE S.r.l. (IT) | 1992-01-08 | — | — | EP | claimed |
| JP-3290228-A | — | — | None | — | — | JP | disclosed |
| JP-6087930-A | — | — | None | — | — | JP | disclosed |
| CN-115516022-B | Strong elastic bicomponent fibers with unique hand feel | 金伯利-克拉克环球有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117616055-A | Polyethylene copolymers with broad short chain branching distribution | 格雷斯公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-116745997-A | Antenna module for 5G system | 提克纳有限责任公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116728919-A | Laterally extensible nonwoven composites | 金伯利-克拉克环球有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116648477-A | Fiber reinforced propylene polymer compositions | 提克纳有限责任公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-1051735-A | Catalyst for producing semi-isotactic polypropylene | FINA TECHNOLOGY (US) | 1991-05-29 | — | — | CN | disclosed |
| EP-0423101-A2 | Catalyst for producing hemiisotactic polypropylene | FINA TECHNOLOGY, INC. (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0412416-A1 | A copolymer of propylene and butene | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-13 | — | — | EP | disclosed |
| EP-0405201-A2 | Polypropylene resin compositions of high syndiotacticity and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0403866-A1 | Novel Poly-alfa-olefins | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-12-27 | — | — | EP | disclosed |
| CN-1046909-A | SYNDIOTACTIC POLYPROPYLENE COPOLYMER | MITSUI TOATSU CHEMICALS (JP) | 1990-11-14 | — | — | CN | disclosed |
| CN-1046534-A | The alpha-olefinic polymer of syndiotactic structure | HIMONT INC (US) | 1990-10-31 | — | — | CN | disclosed |