Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815328 | 0.93 | ALDH1A1 (0.48) | ALDH1A1CYP19A1LMNACYP1A2CYP2C19 | |
| SCHEMBL10419910 | 0.80 | VCAM1 (0.44) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10421681 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9CYP2C19FLT1 | |
| SCHEMBL13865451 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP19A1LMNACYP1A2CYP2C19 | |
| SCHEMBL28148370 | 0.78 | HSPB1 (0.51) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL4797038 | 0.77 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL9242359 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP19A1LMNACYP1A2CYP2C19 | |
| SCHEMBL10421613 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| Acetonitrile SCHEMBL27378482 | 0.76 | CYP1A2 (0.55) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28293014 | 0.76 | CYP1A2 (0.47) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |