Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 12/20 | 0.92 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.92 |
| ▸ | MEN1 | O00255 | 2/20 | 0.92 |
| ▸ | NPC1 | O15118 | 2/20 | 0.92 |
| ▸ | USP2 | O75604 | 2/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.92 |
| ▸ | LMNA | P02545 | 2/20 | 0.92 |
| ▸ | POLB | P06746 | 2/20 | 0.92 |
| ▸ | GAA | P10253 | 2/20 | 0.92 |
| ▸ | MAPT | P10636 | 2/20 | 0.92 |
| ▸ | THRB | P10828 | 2/20 | 0.92 |
| ▸ | HPGD | P15428 | 2/20 | 0.92 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.92 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.92 |
| ▸ | BLM | P54132 | 2/20 | 0.92 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.92 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.92 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.92 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gossypol SCHEMBL352576 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL26123198 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL30260519 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL9738017 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL29798874 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL29355719 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL3939 | 0.96 | MCL1 (1.00) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL28196907 | 0.95 | MCL1 (0.97) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL28138847 | 0.95 | MCL1 (0.97) | MCL1KDM4EMEN1NPC1USP2 | |
| Gossypol SCHEMBL23014699 | 0.94 | MCL1 (0.97) | MCL1KDM4EMEN1NPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115598232-A | Gossypol solution standard substance and preparation method and detection method thereof | 北京活力源科技有限责任公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115598232-A | Gossypol solution standard substance and preparation method and detection method thereof | 北京活力源科技有限责任公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115598232-A | Gossypol solution standard substance and preparation method and detection method thereof | 北京活力源科技有限责任公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| US-20230011770-A1 | LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-01-12 | — | — | US | disclosed |
| CN-109486849-B | CPR and CYP9A12 double-gene co-expression recombinant vector and preparation method and application thereof | 石河子大学 | 2022-11-04 | — | — | CN | disclosed |
| EP-4073066-A2 | LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION | University of Pittsburgh - of the Commonwealth System of Higher Education (US) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021119583-A2 | LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-06-17 | — | — | WO | disclosed |
| CN-109486849-A | CPR and CYP9A12 double gene coexpression recombinant vector and its preparation method and application | 石河子大学 | 2019-03-19 | — | — | CN | disclosed |
| US-7557251-B2 | Production of gossypol co-crystals | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-07-07 | — | — | US | disclosed |
| CN-101454269-A | Production of gossypol co-crystals | UNIV MICHIGAN (US) | 2009-06-10 | — | — | CN | disclosed |
| EP-2007706-A2 | PRODUCTION OF GOSSYPOL CO-CRYSTALS | The Regents of the University of Michigan (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20080021110-A1 | Production of gossypol co-crystals | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-01-24 | — | — | US | disclosed |
| WO-2007126840-A2 | PRODUCTION OF GOSSYPOL CO-CRYSTALS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-11-08 | — | — | WO | disclosed |
| US-6773727-B1 | LOW CONCENTRATION; INCREASING EFFICIENCY OF INSECTICIDES; TERMITES, FIRE ANTS, COCKROACHES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2004-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230011770-A1 | LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION | LGALS4, LGALS9, LGALS3 | MCL1 214/4885KDM4E 1125/4885MEN1 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.