Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739660 | 0.81 | TDO2 (0.61) | TDO2L3MBTL1LMNAMAPT | |
| SCHEMBL6727622 | 0.79 | ABL1 (0.46) | HPGDALDH1A1BCL2L1HSD17B10CASP3 | |
| SCHEMBL19367722 | 0.75 | ALDH1A1 (0.51) | HPGDALDH1A1HSD17B10TDO2SMN1; SMN2 | |
| SCHEMBL19367745 | 0.74 | KMT2A (0.44) | HPGDALDH1A1BCL2L1HSD17B10CASP3 | |
| SCHEMBL17532958 | 0.74 | TDO2 (0.58) | HPGDALDH1A1BCL2L1HSD17B10CASP3 | |
| SCHEMBL6764765 | 0.73 | SMN1; SMN2 (0.45) | HPGDALDH1A1BCL2L1HSD17B10CASP3 | |
| SCHEMBL23596603 | 0.71 | TDO2 (0.46) | HPGDALDH1A1HSD17B10TDO2SMN1; SMN2 | |
| SCHEMBL23596950 | 0.71 | TDO2 (0.46) | HPGDALDH1A1HSD17B10TDO2SMN1; SMN2 | |
| 2-Phenylphenol SCHEMBL6281141 | 0.71 | ALDH1A1 (0.94) | HPGDALDH1A1BCL2L1HSD17B10CASP3 | |
| SCHEMBL13344638 | 0.71 | TDO2 (0.60) | HPGDALDH1A1BCL2L1HSD17B10CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156635-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS | GILLESPIE PAUL | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156635-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS | GYS2, GYS1, GSK3A | HPGD 1332/4885ALDH1A1 633/4885BCL2L1 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.