SCHEMBL4448640

SCHEMBL4448640

O=C(O)/C=C(/CC1CO1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
TSHR P16473 1/20 0.45
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449754 1.00 KDM4E (0.45) KDM4ETSHRCYP1A2CYP2D6CYP2C9
SCHEMBL16556075 1.00 KDM4E (0.45) KDM4ETSHRCYP1A2CYP2D6CYP2C9
SCHEMBL29391774 0.82 MGLL (0.43) KDM4ETSHR
SCHEMBL29393821 0.82 MGLL (0.43) KDM4ETSHR
SCHEMBL1628484 0.81 GRIK1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL5715996 0.81 GRIK1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1899378 0.81 GRIK1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL6036509 0.80 KDM4E (0.42) KDM4ETSHR
SCHEMBL8902172 0.79 KDM4E (0.31) KDM4ETSHR
SCHEMBL17599742 0.79 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3386744-B1 MULTILAYER STRUCTURE COMPRISING A LAYER CONTAINING A FLUOROPOLYMER AND ACRYLIC COPOLYMER - ASSOCIATED PRODUCTION METHOD AND TUBE ARKEMA FRANCE (FR) 2020-04-08 EP claimed
CN-109054632-A A kind of water-fast weather-proof composite powder coatings and preparation method thereof 宁波双人新材料有限公司 2018-12-21 CN claimed
CN-108640849-A Preparation method of ultraviolet-curing terpene-based dendritic epoxy acrylate 南京工业大学 2018-10-12 CN claimed
EP-2883925-B1 Polypropylene based composition REPSOL SA (ES) 2016-10-05 EP claimed
EP-1537989-B1 Use of a tube comprising a fluoropolymer grafted by irradiation for the fuel transport in a gas station ARKEMA FRANCE (FR) 2014-12-24 EP claimed
EP-2601229-B1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS AMYRIS INC (US) 2013-10-16 EP claimed
EP-1928927-B1 POLYURETHANE-BASED GEL MASSES, THEIR PRODUCTION AND USE BAYER MATERIALSCIENCE AG (DE) 2009-06-17 EP claimed
US-12584003-B2 Compositions comprising LDPE, polypropylene and functionalised polyolefins BOREALIS AG (AT) 2026-03-24 US disclosed
EP-3969512-B1 POLYMER COMPOSITIONS COMPRISING MIXTURES OF POLYOLEFINS BOREALIS GMBH (AT) 2026-03-18 EP disclosed
US-12391824-B2 Polymer compositions comprising mixtures of polyolefins BOREALIS AG (AT) 2025-08-19 US disclosed
EP-3969524-B1 COMPOSITIONS COMPRISING LDPE, POLYPROPYLENE AND FUNCTIONALISED POLYOLEFINS BOREALIS GMBH (AT) 2025-08-13 EP disclosed
US-20230131086-A1 POLYMER COMPOSITIONS COMPRISING MIXTURES OF POLYOLEFINS BOREALIS AG (AT) 2023-04-27 US disclosed
US-20220235211-A1 COMPOSITIONS COMPRISING LDPE AND FUNCTIONALISED POLYOLEFINS BOREALIS AG (AT) 2022-07-28 US disclosed
CN-1152278-A Lithographic form plate TORAY INDUSTRIES (JP) 1997-06-18 CN disclosed
EP-0234918-B1 OPTICAL FIBRE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-21 EP disclosed
EP-0286734-B1 LINEAR LOW DENSITY POLYETHYLENE GRAFT POLYMERS, THEIR PREPARATION AND THEIR USES DSM N.V. (NL) 1992-12-09 EP disclosed
EP-0484273-A1 Poly(aryene sulphide) compositions CIBA-GEIGY AG (CH) 1992-05-06 EP disclosed
US-5018828-A Core of polycarbonate or glass and cladding of polymethylpentene MITSUI PETROCHEMCIAL INDUSTRIES, LTD. (JP) 1991-05-28 US disclosed
EP-0286734-A1 Linear low density polyethylene graft polymers, their preparation and their uses DSM N.V. (NL) 1988-10-19 EP disclosed
EP-0234918-A2 Optical fibre MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584003-B2 Compositions comprising LDPE, polypropylene and functionalised polyolefins LCP1, PLOD1, ILK KDM4E 1195/4885TSHR 4554/4885CYP1A2 2149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.