SCHEMBL4449754

SCHEMBL4449754

O=C(O)C=C(CC1CO1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
TSHR P16473 1/20 0.45
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4448640 1.00 KDM4E (0.45) KDM4ETSHRCYP1A2CYP2D6CYP2C9
SCHEMBL16556075 1.00 KDM4E (0.45) KDM4ETSHRCYP1A2CYP2D6CYP2C9
SCHEMBL29391774 0.82 MGLL (0.43) KDM4ETSHR
SCHEMBL29393821 0.82 MGLL (0.43) KDM4ETSHR
SCHEMBL1628484 0.81 GRIK1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL5715996 0.81 GRIK1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1899378 0.81 GRIK1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL6036509 0.80 KDM4E (0.42) KDM4ETSHR
SCHEMBL8902172 0.79 KDM4E (0.31) KDM4ETSHR
SCHEMBL17599742 0.79 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584003-B2 Compositions comprising LDPE, polypropylene and functionalised polyolefins BOREALIS AG (AT) 2026-03-24 US disclosed
EP-3969512-B1 POLYMER COMPOSITIONS COMPRISING MIXTURES OF POLYOLEFINS BOREALIS GMBH (AT) 2026-03-18 EP disclosed
US-12391824-B2 Polymer compositions comprising mixtures of polyolefins BOREALIS AG (AT) 2025-08-19 US disclosed
EP-3969524-B1 COMPOSITIONS COMPRISING LDPE, POLYPROPYLENE AND FUNCTIONALISED POLYOLEFINS BOREALIS GMBH (AT) 2025-08-13 EP disclosed
US-20230131086-A1 POLYMER COMPOSITIONS COMPRISING MIXTURES OF POLYOLEFINS BOREALIS AG (AT) 2023-04-27 US disclosed
US-20220235211-A1 COMPOSITIONS COMPRISING LDPE AND FUNCTIONALISED POLYOLEFINS BOREALIS AG (AT) 2022-07-28 US disclosed
US-20220204734-A1 COMPOSITIONS COMPRISING LDPE, POLYPROPYLENE AND FUNCTIONALISED POLYOLEFINS BOREALIS AG (AT) 2022-06-30 US disclosed
WO-2020229658-A1 COMPOSITIONS COMPRISING LDPE, POLYPROPYLENE AND FUNCTIONALISED POLYOLEFINS BOREALIS AG (AT) 2020-11-19 WO disclosed
WO-2020229659-A1 COMPOSITIONS COMPRISING LDPE AND FUNCTIONALISED POLYOLEFINS BOREALIS AG (AT) 2020-11-19 WO disclosed
WO-2020229657-A1 POLYMER COMPOSITIONS COMPRISING MIXTURES OF POLYOLEFINS BOREALIS AG (AT) 2020-11-19 WO disclosed
CN-101977949-A Polymeric compositions for plastic strapping BASF CORP 2011-02-16 CN disclosed
US-7612131-B2 Flame-retardant resin composition WINTECH POLYMER LTD. (JP) 2009-11-03 US disclosed
US-20080167406-A1 FLAME-RETARDANT RESIN COMPOSITION WINTECH POLYMER, LTD. (JP) 2008-07-10 US disclosed
EP-1935944-A2 Flame-retardant resin composition Wintech Polymer Ltd. (JP) 2008-06-25 EP disclosed
US-7053167-B2 Silsesquioxane derivative having functional group CHISSO CORPORATION (JP) 2006-05-30 US disclosed
US-20060089504-A1 Silsesquioxane derivative having functional group ITO KENYA 2006-04-27 US disclosed
US-20040068074-A1 Production process for silsesquioxane derivative having functional group and silsesquioxane derivative JNC CORPORATION (JP) 2004-04-08 US disclosed
EP-0234918-B1 OPTICAL FIBRE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-21 EP disclosed
US-5018828-A Core of polycarbonate or glass and cladding of polymethylpentene MITSUI PETROCHEMCIAL INDUSTRIES, LTD. (JP) 1991-05-28 US disclosed
EP-0234918-A2 Optical fibre MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060089504-A1 Silsesquioxane derivative having functional group SFXN1, STS, SRM KDM4E 293/4885TSHR 3118/4885CYP1A2 544/4885
US-12584003-B2 Compositions comprising LDPE, polypropylene and functionalised polyolefins LCP1, PLOD1, ILK KDM4E 1195/4885TSHR 4554/4885CYP1A2 2149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.