Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523682 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL4402455 | 0.77 | HSPD1 (0.40) | ALDH1A1 | |
| SCHEMBL3713421 | 0.76 | CAMK2A (0.36) | ALDH1A1 | |
| SCHEMBL5371980 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8507314 | 0.75 | HSPD1 (0.42) | ALDH1A1 | |
| SCHEMBL9513981 | 0.75 | HSPD1 (0.42) | ALDH1A1 | |
| SCHEMBL3627972 | 0.75 | MAPT (0.42) | ABCC4MAPTLPAR3LPAR2ALDH1A1 | |
| SCHEMBL3223653 | 0.75 | HSPD1 (0.42) | ALDH1A1 | |
| SCHEMBL8505820 | 0.75 | HSPD1 (0.42) | ALDH1A1 | |
| SCHEMBL21068602 | 0.75 | MAPT (0.42) | ABCC4MAPTLPAR3LPAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | SRM, SMURF1, SLC39A14 | ABCC4 2000/4885MAPT 2415/4885LPAR3 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.