Phenol

Phenol

SCHEMBL4449486

C1CC[SiH2]OC1.C=CCOc1ccc(O)cc1.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 2/20 0.39
DRD2 P14416 1/20 0.39
DRD3 P35462 1/20 0.39
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HIF1A Q16665 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 1/20 0.36
MGAM O43451 3/20 0.36
GAA P10253 3/20 0.36
SI P14410 3/20 0.36
MGAM2 Q2M2H8 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL8208774 0.81 LMNA (0.55) DRD4DRD2DRD3LMNACYP1A2
Chavicol SCHEMBL4444832 0.81 XDH (0.34) CYP1A2MAPTPOLBGAAALDH2
Phenol SCHEMBL6858847 0.79 CA12 (0.44) NPC1ESR1ESR2CA12CA1
Phenol SCHEMBL9243036 0.79 CA12 (0.44) NPC1ESR1ESR2CA12CA1
Phenol SCHEMBL2420081 0.79 CA12 (0.44) NPC1ESR1ESR2CA12CA1
4-Vinylphenol SCHEMBL4451038 0.79 ALDH1A1 (0.37) RAB9AMGAMGAASIMGAM2
2-Allylphenol SCHEMBL4453152 0.77 GABRA1 (0.36) LMNAMAPTPOLBGAAKDM4E
Phenol SCHEMBL7769420 0.76 MGAM (0.50) DRD4DRD2DRD3LMNACYP1A2
Phenol SCHEMBL11312694 0.76 LMNA (0.47) DRD4DRD2DRD3LMNACYP1A2
Chavicol SCHEMBL4605750 0.74 XDH (0.38) CYP1A2PTGS1MAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937693-A1 SILOXANE BISCHLOROFORMATES General Electric Company (US) 2008-07-02 EP claimed
US-20070093629-A1 Siloxane bishchloroformates GENERAL ELECTRIC COMPANY (US) 2007-04-26 US claimed
WO-2007037888-A1 SILOXANE BISCHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2007-04-05 WO claimed
US-6780956-B2 FOR CONTROLLING PHYSICAL PROPERTIES OF POLYCARBONATESILOXANE COPOLYMERS; FOR PRODUCTION OF OPTICAL DISKS GENERAL ELECTRIC COMPANY 2004-08-24 US claimed
US-20030065122-A1 Method of making silicone copolycarbonates having random and blocky substructures GENERAL ELECTRIC COMPANY 2003-04-03 US claimed
WO-2009035857-A1 COMPOSITION AND ASSOCIATED METHOD SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-03-19 WO disclosed
US-20090069512-A1 COMPOSITION AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2009-03-12 US disclosed
EP-1945693-A1 POLYARYLATE-SILOXANE COPOLYMERS Momentive Performance Materials Inc. (US) 2008-07-23 EP disclosed
EP-1937693-A1 SILOXANE BISCHLOROFORMATES General Electric Company (US) 2008-07-02 EP disclosed
US-20070093629-A1 Siloxane bishchloroformates GENERAL ELECTRIC COMPANY (US) 2007-04-26 US disclosed
WO-2007047083-A1 POLYARYLATE-SILOXANE COPOLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-26 WO disclosed
US-20070083026-A1 Polyarylate-siloxane copolymers GENERAL ELECTRIC COMPANY (US) 2007-04-12 US disclosed
WO-2007037888-A1 SILOXANE BISCHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2007-04-05 WO disclosed
US-6492481-B1 THE SILICONE COPOLYCARBONATES CONTAIN RESIDUES OF SILICONE CONTAINING AND NONSILICONE CONTAINING BISPHENOLS AND HAVE PROPERTIES PARTICULARLY SUITED FOR USE IN HIGH DENSITY OPTICAL DATA STORAGE MEDIA. THE PROPERTIES OF SUBSTANTIALLY SINGLE GENERAL ELECTRIC COMPANY 2002-12-10 US disclosed
EP-1235872-A1 SUBSTANTIALLY SINGLE PHASE SILICONE COPOLYCARBONATES, METHODS, AND OPTICAL ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-09-04 EP disclosed
WO-2002004545-A1 SUBSTANTIALLY SINGLE PHASE SILICONE COPOLYCARBONATES, METHODS, AND OPTICAL ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-01-17 WO disclosed