Amolanone

Amolanone

SCHEMBL24473

CCN(CC)CC[C@@]1(c2ccccc2)C(=O)Oc2ccccc21

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.40
DRD2 P14416 1/20 0.40
PRCP P42785 2/20 0.37
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.36
SLC6A9 P48067 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
CHRM2 P08172 3/20 0.34
CHRM1 P11229 2/20 0.34
KDM4E B2RXH2 1/20 0.34
SLC22A1 O15245 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amolanone SCHEMBL24472 1.00 SIGMAR1 (0.40) SIGMAR1DRD2PRCPALDH1A1MEN1
Amolanone SCHEMBL29615034 1.00 SIGMAR1 (0.40) SIGMAR1DRD2PRCPALDH1A1MEN1
SCHEMBL4449571 0.82 MMP2 (0.48) MEN1KMT2APOLBSLC6A9KDM4E
SCHEMBL3897034 0.80 MMP2 (0.56) MEN1KMT2ATDP1MMP2MMP3
SCHEMBL3896300 0.80 MMP2 (0.56) MEN1KMT2ATDP1MMP2MMP3
SCHEMBL10622542 0.77 SIGMAR1 (0.38) SIGMAR1ALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL10481339 0.74 PKM (0.54) ALDH1A1KMT2ASLC6A9TSHR
SCHEMBL28941602 0.74 SMN1; SMN2 (0.34) ALDH1A1MEN1KMT2APOLBLMNA
SCHEMBL10481376 0.71 PKM (0.41) ALDH1A1KMT2ASLC6A9LMNA
SCHEMBL10481331 0.70 SLC6A9 (0.41) ALDH1A1KMT2ASLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT UNIV KOREA RES & BUS FOUND (KR) 2026-04-30 US claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 WO claimed
US-12419619-B2 Aspiration device YALE UNIVERSITY (US) 2025-09-23 US claimed
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics BIOPOLIMERI S.R.L. (IT) 2025-06-17 US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 US claimed
EP-4362994-B1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S R L (IT) 2025-03-12 EP claimed
EP-3703802-B9 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-12-04 EP claimed
EP-3703802-B1 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-10-16 EP claimed
US-20240293311-A1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S.R.L. (IT) 2024-09-05 US claimed
US-20240261464-A1 POWDER FORMULATION FOR TISSUE REPAIR, PREPARATION METHOD THEREFOR, AND INJECTABLE COMPOSITION FOR TISSUE REPAIR, COMPRISING SAME SAMYANG HOLDINGS CORPORATION (KR) 2024-08-08 US claimed
US-20030027833-A1 Compositions and delivery systems for administration of a local anesthetic agent CORIUM INTERNATIONAL, INC. 2003-02-06 US claimed
WO-2002089849-A1 COMPOSITIONS AND DELIVERY SYSTEMS FOR ADMINISTRATION OF A LOCAL ANESTHETIC AGENT CORIUM INTERNATIONAL (US) 2002-11-14 WO claimed
US-6432986-B2 INTRANOSALLY ADMINISTERING OF ANESTHETICS BHL PATENT HOLDINGS LLC 2002-08-13 US claimed
US-20010055607-A1 COMPOSITIONS, KITS, AND METHODS FOR INHIBITING CEREBRAL NEUROVASCULAR DISORDERS AND MUSCULAR HEADACHES BHL PATENT HOLDINGS LLC 2001-12-27 US claimed
WO-2001080797-A1 MEDICATED WRAP HYSON MORTON I (US) 2001-11-01 WO claimed
WO-2001043733-A2 COMPOSITIONS, KITS, APPARATUS, AND METHODS FOR INHIBITING CEPHALIC INFLAMMATION LEVIN BRUCE H (US) 2001-06-21 WO claimed
US-20010004644-A1 Compositions, kits, apparatus, and methods for inhibiting cephalic inflammation LEVIN BRUCE H (US) 2001-06-21 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010055607-A1 COMPOSITIONS, KITS, AND METHODS FOR INHIBITING CEREBRAL NEUROVASCULAR DISORDERS AND MUSCULAR HEADACHES TNNC1, KIT, PDE3A SIGMAR1 3960/4885DRD2 4209/4885PRCP 2597/4885
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics CD44, HCAR3, HCAR2 SIGMAR1 3401/4885DRD2 2381/4885PRCP 4020/4885
US-20010004644-A1 Compositions, kits, apparatus, and methods for inhibiting cephalic inflammation CXCR5, CCL5, C5AR2 SIGMAR1 1992/4885DRD2 3524/4885PRCP 932/4885
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT CES2, DAGLA, ACHE SIGMAR1 353/4885DRD2 189/4885PRCP 3580/4885
US-20240293311-A1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS CD44, HCAR3, HCAR2 SIGMAR1 3401/4885DRD2 2381/4885PRCP 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.