Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884767 | 0.86 | MMP8 (0.51) | SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL6156033 | 0.86 | MMP8 (0.51) | SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL4881722 | 0.86 | MMP8 (0.51) | SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL4881723 | 0.86 | MMP8 (0.51) | SMN1; SMN2KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL4881666 | 0.84 | PIN1 (0.50) | SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL16746620 | 0.84 | NPC1 (0.50) | ALDH1A1SMN1; SMN2CHRM1CHRM3CHRM2 | |
| SCHEMBL5072148 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4ECHRM1CHRM3 | |
| SCHEMBL9187724 | 0.80 | LMNA (0.62) | ALDH1A1SMN1; SMN2KDM4ECHRM1CHRM3 | |
| SCHEMBL15897196 | 0.78 | KDM4E (0.49) | ALDH1A1SMN1; SMN2KDM4ECHRM1CHRM3 | |
| SCHEMBL15896744 | 0.78 | KDM4E (0.49) | ALDH1A1SMN1; SMN2KDM4ECHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029563-A1 | SEMI-SYNTHETIC ROUTE FOR THE PREPARATION OF PACLITAXEL, DOCETAXEL AND 10-DEACETYLBACCATIN III FROM 9-DIHYDRO-13-ACETYLBACCATIN III | 6570763 Canada Inc. (CA) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007143839-A1 | SEMI-SYNTHETIC ROUTE FOR THE PREPARATION OF PACLITAXEL, DOCETAXEL AND 10-DEACETYLBACCATIN III FROM 9-DIHYDRO-13-ACETYLBACCATIN III | 6570763 CANADA INC. (CA) | 2007-12-21 | — | — | WO | disclosed |