SCHEMBL4450231

SCHEMBL4450231

Clc1ccc(Cl)c(-c2cccc(Cl)c2Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 2/20 0.44
PTPN1 P18031 1/20 0.43
TP53 P04637 1/20 0.42
HTR2B P41595 1/20 0.41
PDE4D Q08499 1/20 0.41
S100A4 P26447 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40
GABRA6 Q16445 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381603 0.84 PTPN1 (0.56) PTPN1TP53HTR2BPDE4DS100A4
SCHEMBL29416774 0.84 PTPN1 (0.56) PTPN1TP53HTR2BPDE4DS100A4
SCHEMBL29983105 0.84 PTPN1 (0.56) PTPN1TP53HTR2BPDE4DS100A4
SCHEMBL4449749 0.83 AHR (0.52) P2RX7TP53S100A4SMN1; SMN2HPGD
SCHEMBL4459079 0.82 AHR (0.52) TP53HTR2BPDE4DS100A4IDO1
SCHEMBL2502453 0.82 TSHR (0.48) P2RX7TP53SMN1; SMN2IDO1NUDT1
SCHEMBL440944 0.81 TP53 (0.61) PTPN1TP53HTR2BPDE4DS100A4
SCHEMBL440943 0.81 TSHR (0.52) P2RX7IDO1NOTUMNUDT1TSHR
SCHEMBL29364307 0.81 TP53 (0.61) PTPN1TP53HTR2BPDE4DS100A4
SCHEMBL4456505 0.80 ALDH1A1 (0.48) P2RX7IDO1NOTUMNUDT1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115524428-B Method for measuring indicative polychlorinated biphenyl in food 江苏微谱检测技术有限公司 2024-08-27 CN claimed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN claimed
CN-115524428-A Method for measuring indicative polychlorinated biphenyl in food 江苏微谱检测技术有限公司 2022-12-27 CN claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-119875009-A Preparation method of multi-template molecularly imprinted polymer for selectively adsorbing multiple pigments and application of multi-template molecularly imprinted polymer in solid-phase extraction packing 宁波大学 2025-04-25 CN disclosed
CN-119519447-A Voltage doubling circuit module, high-voltage power supply, X-ray generator and CT equipment 同方威视技术股份有限公司 2025-02-25 CN disclosed
CN-118556221-A Display device LS电气株式会社 2024-08-27 CN disclosed
CN-115524428-B Method for measuring indicative polychlorinated biphenyl in food 江苏微谱检测技术有限公司 2024-08-27 CN disclosed
CN-106799952-B Control method and device of vehicle-mounted air purifier 杭州联络互动信息科技股份有限公司 2024-01-16 CN disclosed
CN-219874242-U Cabinet power supply device 阿优维科技(东莞)有限公司 2023-10-20 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN disclosed
CN-115295337-A Double-power-supply circuit, method and circuit breaker 德力西电气有限公司 2022-11-04 CN disclosed
CN-217390529-U Novel bean grinder 绍兴市川弘科技有限公司 2022-09-09 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20170001052-A1 METHOD FOR ACTIVATING OXYGENASE-CONTAINING COMPOSITION AND CONTAMINANT DETOXIFICATION METHOD AND DEVICE BASED ON SAME TAKAHATA ELECTRONICS CORPORATION (JP) 2017-01-05 US disclosed
US-20160279456-A1 POLYCHLORINATED BIPHENYL DETOXIFYING COMPLEX COMPOSITION AND METHOD FOR MANUFACTURING SAME NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) 2016-09-29 US disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed