SCHEMBL8505753

SCHEMBL8505753

CCCC(=O)OC1CC(=O)NC1=O.O=C1C=CC(=O)N1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.38
CYP19A1 P11511 2/20 0.35
NLRP3 Q96P20 2/20 0.34
NPSR1 Q6W5P4 3/20 0.33
LMNA P02545 3/20 0.33
MAPT P10636 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
CRBN Q96SW2 3/20 0.32
DDB1 Q16531 2/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551912 0.91 HSD17B10 (0.39) NPC1CYP19A1NLRP3HSD17B10ALDH1A1
SCHEMBL1517935 0.91 PRKCA (0.41) NPC1CYP19A1
SCHEMBL977159 0.82 MAP3K14 (0.38) NPC1CYP19A1LMNAMAPTMEN1
SCHEMBL2099423 0.81 PRKCA (0.47) NPC1CYP19A1
SCHEMBL180318 0.80 PRKCA (0.49)
SCHEMBL3628006 0.80 PRKCA (0.49)
SCHEMBL1332286 0.79 NPC1 (0.36) NPC1CYP19A1LMNAMAPTMEN1
SCHEMBL11095324 0.79 NPC1 (0.36) NPC1CYP19A1LMNAMAPTMEN1
SCHEMBL1886945 0.78 NLRP3 (0.34) NPC1NLRP3HSD17B10ALDH1A1
SCHEMBL20589363 0.77 PRKCA (0.38) CYP19A1LMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214959-B Chip for separating and capturing Ewing sarcoma circulating tumor cells 深圳市儿童医院 2022-08-26 CN claimed
CN-112391263-B Neuroblastoma circulating tumor cell capturing chip and manufacturing method thereof 深圳市儿童医院 2022-05-27 CN claimed
EP-2971064-B1 PROXIMITY ASSAY FOR IN SITU DETECTION OF TARGETS VENTANA MED SYST INC (US) 2019-10-16 EP claimed
EP-4441079-B1 SWITCHABLE POLYPEPTIDE AND ITS USE FOR GENTLE AFFINITY PURIFICATION UNIV OXFORD INNOVATION LTD (GB) 2026-02-11 EP disclosed
EP-4655590-A1 MODIFIED IMMUNO-MOLECULAR ASSAY FOR FASTER BIOMARKER DETECTION BIOMERIEUX (FR) 2025-12-03 EP disclosed
WO-2025245282-A1 COMPOSITIONS AND METHODS FOR DETECTION OF PROTEIN ANALYTES RANGE BIOTECHNOLOGIES, INC. (US) 2025-11-27 WO disclosed
US-12466861-B2 Polypeptide with enhanced rate of spontaneous isopeptide bond formation with its peptide tag partner and uses thereof OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-11-11 US disclosed
US-20250333455-A1 POLYPEPTIDE AND ITS USE IN AFFINITY PURIFICATION UNIV OXFORD INNOVATION LTD (GB) 2025-10-30 US disclosed
US-20250327129-A1 COMPOSITIONS AND METHODS FOR DETECTION OF OVARIAN CANCER MERCY BIOANALYTICS INC (US) 2025-10-23 US disclosed
US-20250297317-A1 COMPOSITIONS AND METHODS FOR DETECTION OF LIVER CANCER MERCY BIOANALYTICS, INC. 2025-09-25 US disclosed
US-20250223649-A1 COMPOSITIONS AND METHODS FOR DETECTION OF LUNG CANCER MERCY BIOANALYTICS, INC. 2025-07-10 US disclosed
US-20220119459-A1 PROTEINS AND PEPTIDE TAGS WITH ENHANCED RATE OF SPONTANEOUS ISOPEPTIDE BOND FORMATION AND USES THEREOF OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2022-04-21 US disclosed
CN-108368538-B Method for generating proximity probes 欧凌科蛋白质公司 2022-03-29 CN disclosed
US-6001580-A DETECTING THE ACTIVATED ISOFORM OF MITOGEN ACTIVATED KINASE; CONTACTING SAMPLE WITH AN ANTIBODY WHICH BINDS AN AMINO ACID SEQUENCE, CONTACTING SAMPLE WITH SECOND ANTIBODY, DETECTING ACTIVE ISOFORM WHICH SPECIFICALLY BINDS TO BOTH ANTIBODIES TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 1999-12-14 US disclosed
EP-0735370-A1 Method for assaying map kinase TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-10-02 EP disclosed
US-5534414-A Process for preparing conjugates consisting of a specific binding partner and a carbohydrate-containing protein BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1996-07-09 US disclosed
EP-0394297-A4 ANTI-RETROVIRAL AGENT 1990-12-27 EP disclosed
WO-1990013562-A1 CHEMICALLY MODIFIED CD4 PEPTIDE FRAGMENTS HAVING ANTI-RETROVIRAL PROPERTIES GENELABS INCORPORATED (US) 1990-11-15 WO disclosed
EP-0394297-A1 ANTI-RETROVIRAL AGENT GENELABS, INCORPORATED (US) 1990-10-31 EP disclosed
WO-1989003813-A1 ANTI-RETROVIRAL AGENT GENELABS INCORPORATED (US) 1989-05-05 WO disclosed