SCHEMBL325404

SCHEMBL325404

O=C1CC(OC(=O)CCCCCN2C(=O)C=CC2=O)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.48
PTGS2 P35354 7/20 0.48
MGLL Q99685 6/20 0.42
FAAH O00519 4/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
PKM P14618 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HSP90AA1 P07900 1/20 0.42
TLR9 Q9NR96 1/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
XBP1 P17861 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RECQL P46063 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
GPR35 Q9HC97 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1413287 0.95 PTGS1 (0.40) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL4450426 0.90 PTGS1 (0.36) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL20589363 0.85 PRKCA (0.38) LMNAMAPTPKMMEN1KMT2A
SCHEMBL30402863 0.81
SCHEMBL28226110 0.81 GSK3A (0.44) ALDH1A1LMNAMAPTPKMHPGD
SCHEMBL3628006 0.79 PRKCA (0.49) PRKCA
SCHEMBL180318 0.79 PRKCA (0.49) PRKCA
SCHEMBL6910643 0.78 PTGS1 (0.51) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL977159 0.78 MAP3K14 (0.38) LMNAMAPTPKMSMN1; SMN2MEN1
SCHEMBL29412566 0.78 MGLL (0.46) PTGS1PTGS2MGLLFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719485-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) Taimed Biologics Inc. (TW) 2026-04-08 EP claimed
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 EP claimed
US-20240398969-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) TAIMED BIOLOGICS INC. (TW) 2024-12-05 US claimed
WO-2024245401-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) TAIMED BIOLOGICS INC. (CN) 2024-12-05 WO claimed
US-20240238432-A1 METHOD FOR GLYCOPROTEIN MODIFICATION HONEYBEAR BIOSCIENCES INC. (TW) 2024-07-18 US claimed
EP-0895082-B1 Bubble jet method for spotting probes on a solid support and method of manufacturing probe arrays. CANON KK (JP) 2003-09-24 EP claimed
US-20030059817-A1 Spotting probe can bind preferentially to target nucleotide squences on solid support; provide liquid containing probe, deposit on solid support, form spot of probe on solid support OKAMOTO TADASHI (JP) 2003-03-27 US claimed
US-20020146715-A1 Spotting probe preferentially bound to solid support; obtain liquid containing probe, apply to surface of solid support, allow stain to form on solid support OKAMOTO TADASHI (JP) 2002-10-10 US claimed
EP-0895082-A2 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array CANON KABUSHIKI KAISHA (JP) 1999-02-03 EP claimed
EP-0367166-A1 Modified interleukin-2 and production thereof Takeda Chemical Industries, Ltd. (JP) 1990-05-09 EP claimed
EP-4719485-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) Taimed Biologics Inc. (TW) 2026-04-08 EP disclosed
US-20260049991-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS GLYPHIC BIOTECHNOLOGIES INC (US) 2026-02-19 US disclosed
US-20260049159-A1 ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES SYNTHIS THERAPEUTICS, INC. (US) 2026-02-19 US disclosed
EP-4655289-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS Glyphic Biotechnologies, Inc. (US) 2025-12-03 EP disclosed
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 EP disclosed
EP-0575906-A2 Sandwich immunoassay of beta-N-acetylglucosaminidase and monoclonal antibody used therein SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1993-12-29 EP disclosed
EP-0328690-A1 METHOD FOR DIAGNOSING CHRONIC ARTICULAR RHEUMATISM FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1989-08-23 EP disclosed
EP-0054685-B1 HYDROPHILIC LATEX PARTICLES, PROCESS FOR THEIR PREPARATION AND THEIR USE Roche Diagnostics GmbH (DE) 1986-07-09 EP disclosed
US-4415700-A EMULSION POLYMERIZATION OF AN UNSATURATED EPOXIDE CARRIERS; IMMUNOASSAY; MEDICAL DIAGNOSIS BOEHRINGER MANNHEIM GMBH (DE) 1983-11-15 US disclosed
EP-0054685-A2 Hydrophilic latex particles, process for their preparation and their use Roche Diagnostics GmbH (DE) 1982-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049991-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS CHAMP1, S100A11, TFIP11 PTGS1 3468/4885PTGS2 3866/4885MGLL 4085/4885
US-20240398969-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) CD4, FCGR3B, FCGR1A PTGS1 4202/4885PTGS2 4455/4885MGLL 4710/4885
US-20240238432-A1 METHOD FOR GLYCOPROTEIN MODIFICATION SIGLEC7, FUT5, FUT6 PTGS1 3702/4885PTGS2 3230/4885MGLL 681/4885
US-20260049159-A1 ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES ALK, CD2, TGFBR2 PTGS1 4395/4885PTGS2 4272/4885MGLL 4413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.