Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
| ▸ | CTSA | P10619 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazine SCHEMBL28381839 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL31550331 | 0.82 | ADORA3 (0.62) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL6013143 | 0.76 | AHR (0.46) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL21035694 | 0.76 | KDM4E (0.55) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL22247986 | 0.76 | AHR (0.46) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL31450995 | 0.76 | AHR (0.45) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL29155467 | 0.76 | AHR (0.46) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL2540914 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2HSD17B10LMNA | |
| Dibenzofuran SCHEMBL8207 | 0.72 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2HSD17B10CYP1A2 | |
| Dibenzofuran SCHEMBL9868133 | 0.72 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107118625-A | Mould the preparation method of rattan article antioxidant coating | 安徽持家汉家居工艺品有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-107099193-A | It is a kind of to mould the preparation method that rattan hanging basket uses coating | 安徽持家汉家居工艺品有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107027836-A | Mould the preparation method of rattan article maintaining agent | 安徽持家汉家居工艺品有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-117224589-A | Traditional Chinese medicine preparation for preventing Alzheimer disease as well as preparation method and application thereof | 深圳华中科技大学研究院 | 2023-12-15 | — | — | CN | disclosed |
| CN-110073510-A | LIGHT-EMITTING ELEMENT, ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | 株式会社半导体能源研究所 | 2019-07-30 | — | — | CN | disclosed |
| CN-107922311-A | Organic electric element compound, organic electric element and its electronic device using it | 德山新勒克斯有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107207488-A | It is used as the bicyclic heteroaryl heteroaryl benzoic acid compounds of retinoic acid receptors β (RAR β) activator | 伦敦皇家学院 | 2017-09-26 | — | — | CN | disclosed |
| CN-107118625-A | Mould the preparation method of rattan article antioxidant coating | 安徽持家汉家居工艺品有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-107099193-A | It is a kind of to mould the preparation method that rattan hanging basket uses coating | 安徽持家汉家居工艺品有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107027836-A | Mould the preparation method of rattan article maintaining agent | 安徽持家汉家居工艺品有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-107027836-A | Mould the preparation method of rattan article maintaining agent | 安徽持家汉家居工艺品有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-106367246-A | Agilawood and pearl soap and preparation method thereof | 广州市香事文化传播有限公司 | 2017-02-01 | — | — | CN | disclosed |
| CN-105168669-A | Traditional Chinese medicine composition for treating otitis media and preparation method and application thereof | GUO WANGSHUI | 2015-12-23 | — | — | CN | disclosed |
| US-9206201-B2 | Boronic acid bearing liphagane compounds as inhibitors of P13K-α and/or β | COUNSEL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-08 | — | — | US | disclosed |
| US-20150051173-A1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-02-19 | — | — | US | disclosed |
| EP-2613775-B1 | N-HYDROXY-BENZAMIDES FOR THE TREATMENT OF CANCER | HOFFMANN LA ROCHE (CH) | 2014-07-30 | — | — | EP | disclosed |
| US-8716285-B2 | N-hydroxy-benzamids for the treatment of cancer | HOFFMANN-LA ROCHE INC. (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2613775-A1 | NOVEL N-HYDROXY-BENZAMIDES FOR THE TREATMENT OF CANCER | F.HOFFMANN-LA ROCHE AG (CH) | 2013-07-17 | — | — | EP | disclosed |
| US-20120065204-A1 | NOVEL N-HYDROXY-BENZAMIDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | US | disclosed |
| WO-2012031993-A1 | NOVEL N-HYDROXY-BENZAMIDES FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051173-A1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B | PIK3CA, PIK3C2A, PI4KA | ALDH1A1 3574/4885MAPT 4359/4885SMN1; SMN2 4468/4885 |
| US-20120065204-A1 | NOVEL N-HYDROXY-BENZAMIDS FOR THE TREATMENT OF CANCER | HNMT, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRAS | ALDH1A1 158/4885MAPT 4852/4885SMN1; SMN2 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.