Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 2/20 | 0.54 |
| ▸ | CTSA | P10619 | 6/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22088585 | 0.90 | CES2 (0.45) | EEF2KCTSAFFAR1 | |
| SCHEMBL15577633 | 0.89 | FFAR1 (0.51) | EEF2KCTSAFFAR1CACNA2D1CACNA1B | |
| SCHEMBL16823437 | 0.89 | FFAR1 (0.51) | EEF2KCTSAFFAR1CACNA2D1CACNA1B | |
| SCHEMBL16823438 | 0.89 | FFAR1 (0.51) | EEF2KCTSAFFAR1CACNA2D1CACNA1B | |
| SCHEMBL3548212 | 0.86 | FFAR1 (0.46) | EEF2KCTSAFFAR1CYP2C19 | |
| SCHEMBL6703313 | 0.85 | CACNA2D1 (0.55) | EEF2KGABBR2GABBR1FFAR1CACNA2D1 | |
| SCHEMBL16853745 | 0.85 | CACNA2D1 (0.55) | EEF2KGABBR2GABBR1FFAR1CACNA2D1 | |
| SCHEMBL22089315 | 0.84 | GABBR2 (0.50) | EEF2KCTSAGABBR2GABBR1FFAR1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL5283373 | 0.84 | GABBR2 (0.59) | GABBR2GABBR1FFAR1POLBMAPT | |
| 3,3-Diphenylpropanoic Acid SCHEMBL66473 | 0.84 | GABBR2 (0.59) | GABBR2GABBR1FFAR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111993-A1 | Process for Preparing Beta-(Fluorophenyl)-Propanoate Ester Derivatives | ASTRAZENECA AB (SE) | 2009-04-30 | — | — | US | disclosed |
| EP-1951652-A1 | PROCESS FOR PREPARING BETA- (FLUOROPHENYL) -PROPANOATE ESTER DERIVATIVES | Astra Zeneca AB (SE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057643-A1 | PROCESS FOR PREPARING BETA- (FLUOROPHENYL) -PROPANOATE ESTER DERIVATIVES | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111993-A1 | Process for Preparing Beta-(Fluorophenyl)-Propanoate Ester Derivatives | ADH1A, ADH1C, ADH5 | EEF2K 1644/4885CTSA 3573/4885GABBR2 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.