Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451612 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL13408956 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL4452865 | 0.82 | RAB9A (0.39) | ALDH1A1NPC1MAPTRAB9AMEN1 | |
| SCHEMBL4452867 | 0.82 | RAB9A (0.39) | ALDH1A1NPC1MAPTRAB9AMEN1 | |
| SCHEMBL1911617 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL1911619 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL8556695 | 0.72 | L3MBTL1 (0.73) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL4462546 | 0.71 | ALOX5 (0.51) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL20888390 | 0.70 | ALDH1A1 (0.70) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL3046343 | 0.70 | ALDH1A1 (0.70) | ALDH1A1HPGDNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |